Systems Biology in Drug Discovery and Development
The first book to focus on comprehensive systems biology asapplied to drug discovery and development
Drawing on real-life examples, Systems Biology in Drug Discoveryand Development presents practical applications of systems biologyto the multiple phases of drug discovery and development. This bookexplains how the integration of knowledge from multiple sources,and the models that best represent that integration, inform thedrug research processes that are most relevant to thepharmaceutical and biotechnology industries.
The first book to focus on comprehensive systems biology and itsapplications in drug discovery and development, it offerscomprehensive and multidisciplinary coverage of all phases ofdiscovery and design, including target identification andvalidation, lead identification and optimization, and clinicaltrial design and execution, as well as the complementary systemsapproaches that make these processes more efficient. It alsoprovides models for applying systems biology to pharmacokinetics,pharmacodynamics, and candidate biomarker identification.
Introducing and explaining key methods and technical approachesto the use of comprehensive systems biology on drug development,the book addresses the challenges currently facing thepharmaceutical industry. As a result, it is essential reading forpharmaceutical and biotech scientists, pharmacologists,computational modelers, bioinformaticians, and graduate students insystems biology, pharmaceutical science, and other relatedfields.
Was andere dazu sagen - Rezension schreiben
Model Construction and Analysis
Simulation of Population Variability in Pharmacokinetics
Applications of Systems Biology Approaches to Target
Lead Identification and Optimization
Systems Modeling Applied to Candidate Biomarker
Simulating Clinical Trials
SYNERGIES WITH OTHER TECHNOLOGIES
Future Outlook for Systems Biology