Advances in Systems Biology

Cover
Lee K. Opresko, Julie M. Gephart, Michaela B. Mann
Springer Science & Business Media, 06.12.2012 - 108 Seiten
This book is based on the proceedings of the inaugural symposium "Northwest Symposium for Systems Biology". Particular focus is on identifying current breakthrough technologies and their application to important model systems. By integrating computational sciences, high-throughput technologies and quantitative biology, this book will advance the understanding of not just the function of individual genes, proteins and smaller molecules like hormones, but also how all of these molecules interact within a cell. This volume will be a collection of presentations on four topics that comprise the scope of the Genomes to Life project recently announced by the Department of Energy. They are four aspects of a system biology approach to understanding microbial communities. These topics include complex microbial systems, gene regulatory networks, molecular machines/ multiprotein complexes and computational techniques.
 

Inhalt

COMPLEX MICROBIAL SYSTEMS
4
2 HIGHTHROUGHPUT TECHNIQUES FOR ANALYZING COMPLEX BACTERIAL COMMUNITIES
5
COMPUTATIONAL METHODS
18
3 A SYSTEMS APPROACH TO DISCOVERING SIGNALING AND REGULATORY PATHWAYS
19
4 GENOME FUNCTIONA VIRUSWORLD VIEW
31
MULTIPROTEIN COMPLEXES
47
AN IDEALPATHWAY FOR SYSTEMS BIOLOGY ANALYSIS
48
6 CONFORMATIONAL SWITCHING IN MUSCLE
60
GENE REGULATORY NETWORKS
83
7 THE INTRICATE WORKINGS OF A BACTERIAL EPIGENETIC SWITCH
84
REGULATION AND INTERFACE WITH CELL BIOLOGY
91
INDEX
106
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