Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders

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Michael Aschner, Lucio G. Costa
Academic Press, 18.06.2015 - 450 Seiten
Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders presents a state-of-the-art review of the effects of environmental contaminants on the development and degeneration of the human nervous system, brought together by world-leading experts in the field. Part One describes the adverse effects that the environment can have on neurological development, and how these effects may exhibit. Specific contaminants and their possible consequences of exposure are addressed (lead, methylmercury, alcohol), as well as specific disorders and the environmental factors associated with them, such as the effect of diet on attention deficit and hyperactivity disorders. Part Two tackles neurodegenerative disorders, specifically addressing their potential neurotoxic origins, and discussing the increasing interest in the effects that early exposure may have in later life. Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders is an invaluable reference for those professionals working in the fields of toxicology, environmental health and neuroscience. - Provides, for the first time, the cutting-edge theory of environmental impacts on both neurodegenerative and neurodevelopmental disorders - Written by an international selection of the world's foremost experts in the field of neurotoxicology - Full-colour throughout, providing accurate and illustrative examples of neurotoxic effects in action - An invaluable reference for those professionals working in the fields of toxicology, environmental health, and neuroscience
 

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Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders
Michael Aschner,Lucio G. Costa
Keine Leseprobe verfügbar - 2015

Häufige Begriffe und Wortgruppen

a-synuclein Acad Sci USA activity adult air pollution alpha-synuclein ALS-PDC altered Alzheimer Alzheimer’s Alzheimer's disease amyloid amyotrophic lateral sclerosis animal models associated astrocytes autism axonal behavioral Biol blood lead levels BMAA Brain Res cell chemicals chronic Clin clinical cognitive cohort cortex cycad cycasin deficits dementia developmental dopamine dopaminergic neurons effects Environ Health Perspect environmental factors epidemiological epigenetic ethanol expression fetal function gene genetic Guam hippocampus human huntingtin Huntington's disease impairment increased induced inhibition interactions l-BMAA lead exposure LRRK2 manganese maternal mechanisms MeHg exposure metabolism methylation methylmercury mice microglia motor mouse model mutations Natl Acad Sci Neurobiol neurodegenerative diseases neurodevelopmental disorders neuroinflammation Neurology Neurosci neurotoxicity Neurotoxicology onset oxidative stress paraquat parkin Parkinson's disease pathology pathways patients PCBs pesticides Pharmacol postnatal potential prenatal Proc Natl Acad protein rats receptor risk factors rodents role SOD1 studies synaptic thyroid hormone tion toxicity Toxicol transgenic

Autoren-Profil (2015)

Dr. Michael Aschner is currently the Harold and Muriel Block Chair in Molecular Pharmacology at Albert Einstein College of Medicine where he is also a Professor in the Departments of Molecular Pharmacology, Neuroscience, and Pediatrics. He is a leading expert in neurotoxicology and neurodevelopmental and neurodegenerative diseases. In addition to serving as a past president of the Society of Toxicology (2022-23), he served on numerous toxicology panels (U.S. EPA and CDC), been an expert reviewer for multiple federal agencies in the US and abroad, and is a member of the Neurotoxicology and Alcohol study section (NIH). He is a past recipient of the prestigious Society of Toxicology Merit Award (2010) and the Distinguished Neurotoxicologist Award (2020). He is a co-editor of the Elsevier series, Advancements in Neurotoxicology in addition to edited other Elsevier titles. He has published numerous articles and has served as an associate editor for multiple high impact factor journals.

Dr. Lucio G. Costa is Professor of Toxicology at the University of Washington in Seattle, and of Pharmacology/Toxicology at the University of Parma Medical School. He received a doctorate in Pharmacology from the University of Milano in 1977, and was a postdoctoral fellow at the University of Texas at Houston. He is a member of several national and international professional organizations, a Fellow of the Academy of Toxicological Sciences, and a European Certified Toxicologist. He received various award for his scientific accomplishments, including the Achievement Award from the Society of Toxicology. He serves in various editorial capacities for several toxicology journals, and is an active manuscript and grant reviewer. Dr. Costa has been the member of dozens of panels and committees at the national and international level dealing with toxicology and risk assessment issues. He has chaired and/or organized symposia at scientific meetings in the United States and internationally. He has been teaching classes in the area of toxicology, neurotoxicology and pharmacology to graduate and medical students for 30 years. He keeps an active research program in the area of neurotoxicology.

Bibliografische Informationen

TitelEnvironmental Factors in Neurodevelopmental and Neurodegenerative Disorders
HerausgeberMichael Aschner, Lucio G. Costa
VerlagAcademic Press, 2015
ISBN012800407X, 9780128004074
Länge450 Seiten
  
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