Periodontal Medicine and Systems Biology

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Brian Henderson, Michael Curtis, Robert Seymour, Nikolaos Donos
John Wiley & Sons, 07.07.2009 - 449 Seiten
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This book provides a systems-based approach to periodontology andoffers a scientific roadmap of the interactions which can lead toperiodontal disease.

The content is divided into five sections. The first introducesthe reader to the concept of systems theory and its mathematicalfoundation. The second section provides the reader with a currentview of periodontal medicine including the microbiology, moleculargenetics, relationship to systemic disease and current and futuretherapies. Periodontitis is caused by members of the oralmicrobiota and the third section provides the reader with variousviews of the relationship of the microbiota to the host. The fourthsection moves from the bacterium to the host and its immuneresponses to altered host: bacteria interactions. The final sectiondeals specifically with bone destruction in periodontitis andbrings the reader up-to-date with the current view of the controlnetwork that exists between mesenchymal cells such as osteoblasts,immune cells and osteoclast precursor cells that controls boneremodelling in health and disease.

 

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Inhalt

COPING WITH
127
PARTI SYSTEMS THEORY AND Gerald W Tannock
139
THE CLINICAL 11 Dynamics of biofilm formation
165
Mechanisms linking periodontitis to 15 The Aggregatibacter formerly
219
A new view of innate immunity for
247
Innate immunity and homeostasis
271
Antimicrobial host defence peptides in resorption
379
Control of inflammation in periodontal 24 Bacterial osteolytic mediators
395
Antigenpresenting cells in chronic Andy Y T Teng
407
Bcell responses in periodontitis 339 Colin R Dunstan
427
Harvey A Schenkein Index
439
Urheberrecht

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Über den Autor (2009)

Brian Henderson is Professor of Cell Biology in the Division ofMicrobial Diseases at UCL Eastman Dental Institute, UniversityCollege London.

Michael A Curtis is Professor of Microbiology and Director ofthe Institute of Cell and Molecular Science at Barts and The LondonSchool of Medicine and Dentistry.

Robert M Seymour is Professor in the UCL Department ofMathematics, University College London.

Professor Nikos Donos is Director of Research Strategy and Headof Periodontology at UCL Eastman Dental Institute, UniversityCollege London.

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