Designs for Life: Molecular Biology After World War IICambridge University Press, 30.05.2002 - 423 Seiten Molecular biology has come to dominate our perceptions of life, health and disease. In the decades following World War II, the Medical Research Council Laboratory of Molecular Biology at Cambridge was a world-renowned center of this emerging discipline. Crick and Watson, among others, did the work that made them famous in this laboratory. Soraya de Chadarevian's important new study is the first to examine the creation and expansion of molecular biology and its place on the postwar governmental agenda through the prism of this remarkable institution. |
Inhalt
Introduction | 1 |
A local study | 2 |
The postwar era | 4 |
The making of a new science | 5 |
Histories of molecular biology | 9 |
Too early too late? | 13 |
Preview | 14 |
POSTWAR RECONSTRUCTION AND BIOPHYSICS | 17 |
Codes maps and sequences | 186 |
Phages in the Cavendish | 195 |
Disciplinary moves | 199 |
Forging links | 201 |
A new name | 206 |
The case for a laboratory of molecular biology | 209 |
Council decision | 216 |
Using the media | 218 |
World War II and the mobilisation of British scientists | 20 |
Active mobilisation | 22 |
Postwar planning | 28 |
The place of science in postwar Britain | 33 |
Science and public display | 43 |
New departures | 48 |
Reconstructing life | 50 |
The need for biophysics | 52 |
The Randall incident | 55 |
Molecular structure | 61 |
War mother of all things? | 69 |
Physics of life versus physics of death | 72 |
War recruits | 78 |
Biophysicists and the transformation of biology | 89 |
Proteins crystals and computers | 98 |
Mad pursuit | 100 |
The Cambridge Mathematical Laboratory | 107 |
From punched card machines to electronic computers | 111 |
Managing data | 118 |
Assessing efficiency | 121 |
Setting the limits | 125 |
A new pace of research | 132 |
Televisual language | 136 |
Models as research tools | 139 |
Publishing models | 146 |
The shape of life | 151 |
A new science | 159 |
BUILDING MOLECULAR BIOLOGY | 161 |
Locating the double helix | 164 |
The debate on the origins | 166 |
Annus mirabilis at Cambridge | 170 |
A cuckoos egg | 172 |
After the double helix | 179 |
University politics | 219 |
Negotiations over site | 225 |
The biologists protest | 228 |
Molecular biology in Cambridge | 232 |
The origins of molecular biology revisited | 236 |
Local strategy or general trend? | 245 |
Biophysics at Kings College London | 248 |
Action concertee and molecular biology in France | 254 |
Benchwork and politics | 261 |
Laboratory cultures | 264 |
Molecular mechanism | 272 |
Boundary objects | 279 |
New technologies | 281 |
In and out of the laboratory | 283 |
Expansion | 285 |
A new laboratory tool | 287 |
Exporting the worm | 291 |
Renegotiating molecular biology | 294 |
On the governmental agenda | 300 |
Brain drain | 304 |
A political role | 307 |
Biology census | 310 |
Biology and Cold War politics | 312 |
Modern biology | 313 |
A Europe of biology | 324 |
The end of an era | 336 |
The party is over | 339 |
From basic to applied? | 345 |
The monoclonal antibody scandal | 353 |
Conclusions | 363 |
Bibliography | 367 |
| 403 | |
Andere Ausgaben - Alle anzeigen
Designs for Life: Molecular Biology after World War II Soraya de Chadarevian Keine Leseprobe verfügbar - 2011 |
Häufige Begriffe und Wortgruppen
A. V. Hill Abir-Am amino acid analysis applied atomic became Bernal biochemistry biologists biomedical biophysics Bodl Bragg Brenner Britain British scientists building Cambridge unit Cavendish cell centre Chadarevian chapter chemistry chymotrypsin collaboration College London committee Crick crystal crystallographers decision Department discussion double helix EDSAC electronic elegans EMBL EMBO established European field funds H. M. Taylor haemoglobin Hartley Hodgkin Huxley important Institute Interview involved John Kendrew Kendrew Papers King's College London Laboratory of Molecular later LMB Archives machine Max Perutz Medical Research Council Mellanby mobilisation molecular biology molecules move MRC Archives MRC unit myoglobin nuclear Olby organisation phage physicists physics political postwar problem programme proposed protein crystallography Randall's role Royal Society Sanger science policy scientific sequence structure of DNA suggested techniques technologies tion University Archives wartime Watson and Crick's worm X-ray crystallography Zuckerman
Beliebte Passagen
Seite 390 - From the structure of antibodies to the diversification of the immune response.