Formal Methods in Systems Biology: First International Workshop, FMSB 2008, Cambridge, UK, June 4-5, 2008, Proceedings
Thisvolumecontainstheproceedingsofthe?rstinternationalmeetingonFormal Methods in Systems Biology, held at Microsoft Research, Cambridge, UK, June 4–5, 2008. While there are several venues that cover computational methods in systems biology,there is to date no single conference that brings together the application of the range of formal methods in biology. Therefore, convening such a meeting could prove extremely productive. The purpose of this meeting was to identify techniques for the speci?cation, development and veri?cation of biological m- els.Italsofocusedonthedesignoftoolstoexecuteandanalyzebiologicalmodels in ways that can signi?cantly advance our understanding of biological systems. As a forum for this discussion we invited key scientists in the area of formal methods to this unique meeting. Although this was a one-o? meeting, we are exploring the possibility of this forming the ?rst of what might become an annual conference. Presentations at the meeting were by invitation only; future meetings are expected to operate on a submission and review basis. The Steering Committee and additional referees reviewed the invited papers. Each submission was evaluated by at least two referees. The volume includes nine invited contributions. Formal Methods in Systems Biology 2008 was made possible by the cont- bution and dedication ofmany people. First of all,we wouldlike to thank allthe authors who submitted papers. Secondly, we would like to thank our additional invited speakers and participants. We would also like to thank the members of the Steering Committee for their valuable comments. Finally, we ackno- edge the help of the administrative and technical sta? at the MicrosoftResearch Cambridge lab.
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Concurrency for Modeling CellCell
Computational Probability for Systems Biology
Design Issues for Qualitative Modelling of Biological Cells with
Combining Intra and Intercellular Dynamics to Investigate Intestinal
Approximating Continuous Systems by Timed Automata
RuleBased Modelling Symmetries Reﬁnements
One Modelling Formalism Simulator Is Not Enough A Perspective
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Formal Methods in Systems Biology: First International Workshop, FMSB 2008 ...
Eingeschränkte Leseprobe - 2008
abstraction action activates addition algorithm allows analysis animation applied approach approximation assume behavior biological bounded bounded asynchrony cascade cell changes channel chemical clock communication complex components Computational concurrent consider continuous crypt cube deﬁned described diﬀerent diﬀerential direction discrete distributed dynamics enabled equations event example execution exists experiments expressions fate ﬁrst formalism front-end function gene given Heidelberg implementation increasing inﬂuence graph inhibits initial interactions interleaving JAMES Journal kinetics matrix mechanism methods molecular molecules move natural networks Note object parallel particular pathway performance Petri nets possible present probability processes production properties protein provides reaction reactive reﬁnement represent rule scheduler Science signal simulation space species speciﬁcation Springer steps stochastic structure Systems Biology techniques theorem tion tool transition values variable