Best Synthetic Methods: Acetylenes, Allenes and Cumulenes

Cover
Lambert Brandsma
Elsevier, 16.12.2003 - 502 Seiten
There is a vast and often bewildering array of synthetic methods and reagents available to organic chemists today. The Best Synthetic Methods series allows any scientist who is interested in the chemical transformations of molecules to choose between all the alternatives and assess their real advantages and limitations. With the emphasis on laboratory use, these volumes represent a comprehensive and practical guide to modern synthetic organic chemistry. Best Synthetic Methods: Acetylenes, Allenes and Cumulenes is the product of the author's many years practical experience and reading of the original literature. It contains a valuable distillation and critical evaluation of the Best Synthetic Methods for the formation and reaction of molecules containing carbon-carbon triple bonds or cumulative carbon-carbon double bonds. A brief review of each area is provided, but the emphasis in all cases is on describing efficient practical methods to effect the transformations described. The reader can therefore use this book to rapidly review and select the best methods of performing a synthetic conversion to create or modify a molecule containing an acetylene, allene or cumulene functionality. In addition, the documentation of a large number of experimental recipes enables the user to synthesise an unsaturated molecule without the need to access to the original literature. - Reviews and evaluates the various methods for the formation and reaction of acetylenes, cumulenes and allenes - Provides detailed practical experimental for many important reactions - General tips and analytical data are provided from the author's own extensive research in this area
 

Inhalt

Chapter 1 Procedures and Equipment
1
Chapter 2 Preparation Purification and Storage of Some Solvents and Reagents
11
Chapter 3 Generation of Metallated Acetylenes Allenes and Cumulenes
25
Chapter 4 Reactions of Metallated Acetylenes and Allenes with Alkylating Agents
85
Chapter 5 Reactions with Aldehydes and Ketones
119
Chapter 6 Carboxylation Acylation and Related Reactions
135
Chapter 7 Silylation Stannylation and Phosphorylation
161
Chapter 8 Sulphenylation and Related Reactions
175
Chapter 13 Aminoalkylation of Acetylenic Compounds
267
Chapter 14 Crosscoupling between 1Alkynes and 1Bromo1alkynes
273
Chapter 15 Copper HalideCatalysed Oxidative Coupling of Acetylenes
281
Chapter 16 Transition MetalsCatalysed Couplings of Acetylenes with sp2Halides
293
Chapter 17 BaseCatalysed Isomerisations of Acetylenic Compounds
319
Chapter 18 Allenic Compounds by 23 and 33Sigmatropic Rearrangements
341
Chapter 19 Miscellaneous Reactions of Acetylenic and Allenic Compounds
353
Chapter 20 Transformation of Functional Groups in Acetylenic and Allenic Compounds
369

Chapter 9 Halogenation of Acetylenes
191
Chapter 10 Acetylenes Allenes and Cumulenes by Elimination Reactions
203
Chapter 11 Cumulenes by Dehalogenation of Geminal Dihalogenocyclopropanes
229
Chapter 12 Acetylenic and Allenic Derivatives by Substitution on sp and sp2Carbon
235
1H and 13CNMR Chemical Shifts of Acetylenic Allenic and Cumulenic Compounds
427
ClassCompoundMethod Index
431
Complementary Subject Index
455
Urheberrecht

Andere Ausgaben - Alle anzeigen

Häufige Begriffe und Wortgruppen

Beliebte Passagen

Seite ii - SAINSBURY: Rodd's Chemistry of Carbon Compounds TROST & FLEMING: Comprehensive Organic Synthesis Journals BIOORGANIC & MEDICINAL CHEMISTRY BIOORGANIC & MEDICINAL CHEMISTRY LETTERS CARBOHYDRATE RESEARCH HETEROCYCLES (distributed by Elsevier) JOURNAL OF SUPRAMOLECULAR CHEMISTRY PHYTOCHEMISTRY TETRAHEDRON TETRAHEDRON: ASYMMETRY TETRAHEDRON LETTERS Full details of all Elsevier Science publications, and a free specimen copy of any Elsevier Science journal, are available on request from your nearest Elsevier...
Seite 12 - In carrying out the dry distillation both of animal and vegetable substances, great care should be taken to keep the temperature as low as possible...

Bibliografische Informationen