Veterinary Clinical Epidemiology, Third Edition

Cover
CRC Press, 10.01.1995 - 304 Seiten
Approaches and techniques of clinical epidemiology have become increasingly prominent in veterinary literature. This second edition of Veterinary Clinical Epidemiology: A Problem-Oriented Approach reflects the increasing recognition of the role of clinical epidemiology by focusing on the application of epidemiologic principles and techniques of problems regularly faced by veterinary practitioners.

Numerous examples from veterinary literature indicate how experience with patients can be used to explore issues of importance in the practice of veterinary medicine while controlling for bias, confounding, and chance. The first part of the book focuses on the application of epidemiology in medical decision-making, while the second part focuses on the epidemiology of disease in populations and outbreak investigation.

Included in this text are a glossary and an extensive bibliography, as well as myriad updates to reflect the expanding use of epidemiologic methodology in clinical research. Veterinary Clinical Epidemiology: A Problem-Oriented Approach serves as both a teaching resource for veterinary epidemiology and a reference on the application of epidemiologic methods in veterinary clinical research.
 

Inhalt

INTRODUCTION
1
DEFINING THE LIMITS OF NORMALITY
13
EVALUATION OF DIAGNOSTIC TESTS
31
USE OF DIAGNOSTIC TESTS
53
MEASURING THE COMMONNESS OF DISEASE
71
RISK ASSESSMENT AND PREVENTION
91
USES OF RISK
93
CASE CONTROL RETROSPECTIVE STUDIES OF RISK
100
STATISTICAL SIGNIFICANCE
145
THE SELECTION OF AN APPROPRIATE STATISTICAL TEST
152
PARAMETRIC AND NONPARAMETRIC TESTS
154
USING A TREE DIAGRAM TO SELECT A STATISTICAL TEST
155
MULTIPLE COMPARISONS
157
SUMMARY
158
MEDICAL ECOLOGY AND OUTBREAK INVESTIGATION
161
OUTBREAK INVESTIGATION
163

PREVALENCE SURVEYS OF RISK
105
BIOLOGICAL PLAUSIBILITY AND CROSSSECTIONAL STUDY DESIGNS
107
SUMMARY
108
MEASURING AND COMMUNICATING PROGNOSES
111
NATURAL HISTORY VERSUS CLINICAL COURSE
112
PROGNOSIS AS A RATE
113
SURVIVAL ANALYSIS
115
COMMUNICATION OF PROGNOSES
125
SUMMARY
127
DESIGN AND EVALUATION OF CLINICAL TRIALS
129
CASE STUDIES
134
SUBGROUPS
141
CLINICAL TRIALS IN PRACTICE
142
SUMMARY
165
MEASURING AND EXPRESSING OCCURRENCE
167
REPORTING DISEASE OCCURRENCE
169
CASE STUDIES
175
SUMMARY
184
ESTABLISHING CAUSE
187
SOURCE AND TRANSMISSION OF DISEASE AGENTS
205
THE COST OF DISEASE
227
GLOSSARY
247
REFERENCES
259
INDEX
269
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