David Paul von Hansemann: Contributions to Oncology: Context, Comments and TranslationsSpringer Science & Business Media, 15.02.2007 - 371 Seiten In 1890, just a few years after the discovery of the chromosomes, David Paul Hansemann, a pathologist-in-training with the famous Rudolph Virchow in Berlin, produced a theory of the pathogenesis of cancer involving the key current concept: that the first change which occurs in cancer is an alteration of the hereditary material of a normal cell at the site where the cancerous process begins. In the process of linking cancer to chromosomal material, Hansemann coined the terms "anaplasia" and "dedifferentiation". These terms have remained the basis of descriptive terms concerning the microscopical appearances of tumours ever since. Nevertheless, despite the popularity of his terminology, Hansemann's ideas were attacked vigorously by almost all proponents of rival theories of the nature of cancer. Partly due to these disputes during his life-time, and partly due to other factors, interest in von Hansemann's ideas diminished during the twentieth century and his works are rarely mentioned today. This book presents translations of all the relevant German texts, and analyses the background and context of Hansemann's theories as well as the reasons why he was almost completely forgotten. It shows that some of Hansemann’s ideas may still be relevant to cancer research today, and that he deserves to be remembered in relation to cancer as Vordenker unter den führenden Denkern seiner Zeit - The foremost of the leading thinkers of his time. |
Inhalt
Chapter | 3 |
Chapter | 12 |
Introduction | 25 |
Embryology | 30 |
Altruism cellular altruism and biologistic sociology | 32 |
Chapter | 41 |
Genetics general considerations | 48 |
Notes to chapter 3 | 54 |
Chapter | 145 |
Chapter | 159 |
Studies on the Specificity the Altruism and the Anaplasia of cells with | 179 |
Hansemanns other articles and books on tumours and related topics | 277 |
On cure and curability 1897g | 283 |
Malignant growths and normal reproductive tissues 1904q | 289 |
What do we know of the origin of malignant tumours? 19051 | 295 |
Atlas of Malignant Tumours 1910k | 302 |
Embryonal theories of cancer | 61 |
51 | 68 |
Chapter | 75 |
Hansemann on mitoses and chromosomes in general | 82 |
Ribbert and the theory of control by connective tissue | 91 |
Beneke Wolff | 101 |
Reviewers in the 1920s and after | 107 |
Why was Hansemann forgotten? other factors | 114 |
of cells | 123 |
Experimental chemotherapy of animals with tumours 1912c | 305 |
On precancerous conditions 1913e | 313 |
Appendix | 319 |
Specificity | 323 |
Bibliography of David Paul von Hansemann | 331 |
347 | |
363 | |
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David Paul Von Hansemann: Contributions to Oncology: Context, Comments and ... Leon P. Bignold,Brian L. D. Coghlan,Hubertus P.A. Jersmann Keine Leseprobe verfügbar - 2007 |