## Stochastic Approaches for Systems BiologyThis textbook focuses on stochastic analysis in systems biology containing both the theory and application. While the authors provide a review of probability and random variables, subsequent notions of biochemical reaction systems and the relevant concepts of probability theory are introduced side by side. This leads to an intuitive and easy-to-follow presentation of stochastic framework for modeling subcellular biochemical systems. In particular, the authors make an effort to show how the notion of propensity, the chemical master equation and the stochastic simulation algorithm arise as consequences of the Markov property.
The text contains many illustrations, examples and exercises to illustrate the ideas and methods that are introduced. Matlab code is also provided where appropriate. Additionally, the cell cycle is introduced as a more complex case study.
Senior undergraduate and graduate students in mathematics and physics as well as researchers working in the area of systems biology, bioinformatics and related areas will find this text useful. |

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### Inhalt

Introduction
| 1 |

Biochemical Reaction Networks
| 23 |

Randomness
| 53 |

Probability and Random Variables
| 75 |

Stochastic Modeling of Biochemical Networks
| 115 |

The 2MA Approach
| 173 |

The 2MA Cell Cycle Model
| 201 |

Hybrid Markov Processes
| 221 |

WetLab Experiments and Noise
| 235 |

References | 245 |

Glossary | 261 |

281 | |

### Andere Ausgaben - Alle anzeigen

Stochastic Approaches for Systems Biology Mukhtar Ullah,Olaf Wolkenhauer Keine Leseprobe verfügbar - 2014 |

Stochastic Approaches for Systems Biology Mukhtar Ullah,Olaf Wolkenhauer Keine Leseprobe verfügbar - 2011 |