## Systems Biology in Practice: Concepts, Implementation and ApplicationJohn Wiley & Sons, 06.05.2005 - 485 Seiten Presenting the main concepts, this book leads students as well as advanced researchers from different disciplines to an understanding of current ideas in the complex field of comprehensive experimental investigation of biological objects, analysis of data, development of models, simulation, and hypothesis generation. It provides readers with guidance on how a specific complex biological question may be tackled: - How to formulate questions that can be answered
- Which experiments to perform
- Where to find information in databases and on the Internet
- What kinds of models are appropriate
- How to use simulation tools
- What can be learned from the comparison of experimental data and modeling results
- How to make testable predictions
The authors demonstrate how mathematical concepts can illuminate the principles underlying biology at a genetic, molecular, cellular and even organism level, and how to use mathematical tools for analysis and prediction. |

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### Inhalt

Biology in a Nutshell | 19 |

Systems Biology in Practice Concepts Implementation and Application | 57 |

Experimental Techniques in a Nutshell | 109 |

Standard Models and Approaches in Systems Biology | 135 |

Signal Transduction | 197 |

Copyright 2005 WILEYVCH Verlag GmbH Co KGaA Weinheim | 201 |

Selected Biological Processes | 225 |

Modeling of Gene Expression | 257 |

Analysis of Gene Expression Data | 289 |

Evolution and Selforganization | 337 |

Data Integration | 367 |

Whats Next? | 387 |

Computerbased Information Retrieval and Examination | 397 |

Modeling Tools | 419 |

451 | |

### Andere Ausgaben - Alle anzeigen

Systems Biology in Practice: Concepts, Implementation and Application Edda Klipp,Ralf Herwig,Axel Kowald,Christoph Wierling,Hans Lehrach Eingeschränkte Leseprobe - 2008 |

Systems Biology in Practice: Concepts, Implementation and Application Edda Klipp,Ralf Herwig,Axel Kowald,Christoph Wierling,Hans Lehrach Keine Leseprobe verfügbar - 2008 |

### Häufige Begriffe und Wortgruppen

active algorithm amino acids Bayesian networks behavior bicluster binding Biochem Biol Boolean networks calculated cDNA cell cycle cellular chromosomes clones cluster column complex computational contains control analysis control coefficients cyclin database defined denotes depends described differential equations distribution dynamics eukaryotic example experimental fragments function gene expression genetic genome GO terms graph hypercycle inhibition inhibitor initial interactions kinase kinetics linear mathematical measure membrane metabolic network metabolite method microarray mitochondria molecular molecules mRNA Nucleic Acids nucleotide optimal organisms oscillations parameters pathways phase plane probability probe processes protein random variables rate constants reaction rate receptor regulation regulatory replication sample SBML SCHUSTER Section sequence signal simulation solution Southern blotting specific statistic steady steady-state flux stochastic stoichiometric matrix structure substrate systems biology technique theorems theory tion transcription factors values vector WESTERHOFF yeast