Evidence-Based Dermatology

Michael Bigby, Andrew Herxheimer, Luigi Naldi, Berthold Rzany, Robert Dellavalle, Yuping Ran, Masutaka Furue
John Wiley & Sons, 05.06.2014 - 680 Seiten
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Be sure your skin-care treatments have strong evidential support

Evidence-based Dermatology, Third Edition takes a unique approach to clinical dermatology by emphasising use of only the highest quality available evidence when treating people with skin diseases.

Beginning with a toolbox introduction to the practice of evidence-based dermatology, it then covers the application of evidence for dermatological treatments across a wide range of ailments, including:

• Common inflammatory skin diseases

• Skin cancer, moles and actinic keratoses

• Infective skin disease, exanthems and infestations

• Disorders of pigmentation

In addition, many of the rarer skin disorders are also included so as to provide comprehensive coverage of the topic.

World-leading experts in dermatology follow a clinical approach for each disease, and as well as providing their expert guidance on the description and diagnosis of dermatologic disorders, they also discuss common dilemmas that clinicians face when considering the best approach to patient management. ‘Key Points’ accompany each chapter to provide a quick review of the most important points.

Clinically oriented and practically focused, Evidence-based Dermatology ensures that your treatments are entirely patient-focused and fully supported by the very latest medical evidence.


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lichen planus Table 28 1
Acute Urticaria
Summary of data from RCTs of the treatment
Treatment of Cutaneous Melanoma
Treatment of Squamous Cell

The Role of Patient and Public
The Cochrane Skin Group
Data Sources Backtothe Individual Patient
Finding the Best Evidence
1 Strength of recommendation taxonomy
The Hazards of Quick Searches
Assessing and Explaining the Evidence
1 Trial reportingand study quality may be related but are not necessarily the same All poorly reported trials reside in the shaded area of uncertainty
1 Quality of evidence in a study of a diagnostic
Critical Appraisal of Diagnostic Studies
Inclusion and Exclusion Criteria
1 Summary of the advantages
Guidelines for Critical Appraisalof Pharmacoeconomic Studies
Comparative Effectiveness Research WhatIt Is and How to Assess ItsQuality
Outcome Measures
see text
Introduction WhatCan We Do with Outcomes?
Qualitative Research and EvidenceBased
1 Methods used in qualitative research
Methods Critical Appraisal and MetaAnalysis
Other Useful Resources
What Are the Patients Values?
1 RCTs of skin cleansers and abrasives
2 Benzoyl peroxide BP doseresponse RCTs
4 Targets of acne therapies
Perioral Dermatitis
Patient Perception
The Primary Preventionof Atopic
Treatment of Psoriasis
1 The results of RCTs evaluating the use of pimecrolimus cream 1 in perioral dermatitis
3 Infliximab
Lichen Planus
Streptococcal CellulitisErysipelas
Melanocytic Nevi
Evidence Summary
Implications for Clinical Practice
Atopic Eczema
Infective Skin Diseases Exanthems
Pityriasis Versicolor
Tinea Capitis
Deep Fungal Infections
Exanthematic Reactions
Herpes Simplex
Cutaneous Leishmaniasis
Head Lice
Seborrheic Dermatitis
The Evidence
Acquired Subepidermal Bullous
SECTION2 Skin Cancer Moles and Actinic
Acne Vulgaris Background Questions
Dermal Fillers
Infantile Hemangiomas
Pruritus in Hematological Diseases
Human Immunodeficiency Virus and Itch
Pruritus in Pregnancy Unrelatedto Skin Diseases
Vulval Lichen sclerosus Erosive Lichen Planus and Vulvodynia
Erosive Lichen Planus
Venous Ulcers
Where Do We Go from Here?
Progress and Future Prospects for Evidence Based Dermatology Acknowledgments
Subject Index

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Über den Autor (2014)

Hywel Williams, MBBS Department of Dermatology, Queen's Medical Centre, University of Nottingham, Nottingham, UK.

Michael Bigby, MD, Department of Dermatology, Harvard Medical School, USA.

Andrew Herxheimer, MBBS, UK Cochrane Centre.

Luigi Naldi, M, Department of Dermatology, Ospedali Riuniti, Bergamo, Italy.

Berthold Rzany, MD, Division of EBM, Klinik fur Dermatologie, Charite-Universitatsmedizin, Berlin, Germany.

Robert Dellavalle, MD, Chief, Dermatology Service, Denver VA Medical Center, USA.

Yuping Ran, MD, Department of Dermatology, Sichuan University, China.

Masutaka Furue, MD, Department of Dermatology, Kyushu University, Japan.

Bibliografische Informationen