Isotope Tracers in Metabolic Research: Principles and Practice of Kinetic AnalysisJohn Wiley & Sons, 18.10.2004 - 488 Seiten In the past few years, the number of applications of tracers for in vivo biomedical studies has greatly increased. New analytical tools at the genetic and protein levels have spurred this growth, opening the door for a deeper understanding of metabolic events. This in turn promises to yield significant advances in the understanding and treatment of human disease. Now fully revised and expanded, Isotope Tracers in Metabolic Research, Second Edition is the established definitive text on stable and radioactive isotope tracers. In unique, multidisciplinary fashion, it presents comprehensive coverage of new methodological, mathematical, and theoretical approaches. This new Second Edition includes:
In this complete guide to performing tracer studies, the authors systematically cover tracer selection, modeling considerations, sample derivitization, mass spectrometry analysis, and data interpretation. Problems and discussion questions highlight key points in each chapter. Isotope Tracers in Metabolic Research, Second Edition offers students and researchers a comprehensive, practical resource for utilizing the latest tracer methodologies. |
Inhalt
CHAPTER 2 | 182 |
AND RADIATION DOSAGES | 259 |
SINGLEPOOL MODEL | 307 |
CHAPTER 13 | 325 |
MULTIPLEPOOL MODELS | 355 |
DETERMINATION OF ISOTOPE | 390 |
419 | |
LABELED WATER METHOD | 449 |