Systems Biology of Tumor Dormancy
This volume is based on the Workshop on Systems Biology of Tumor Dormancy meeting, held July 25th to July 28th, 2011. The first annual CCSB workshop brought together biologists, clinicians, mathematicians, and computer scientists to discuss various aspects of tumor dormancy and develop novel mathematical/computational models with the keynote speakers. Specific topics included the angiogenic switch, immune system interactions, cancer stem cells and signaling.
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Acad Sci USA activation Aguirre-Ghiso angiogenesis angiogenic angiogenic switch anti-angiogenic antibody antigen apoptosis autophagy Biol breast cancer cancer cells cancer dormancy cancer patients Cancer Res cancer stem cells carcinoma cell cycle cell death cellular Clin clinical CTLs cytokines cytotoxic cytotoxic T cells detection disease dormant tumor cells DTCs dynamics effectors equilibrium experimental expression Folkman gene growth factor host immune cells immune response immune system immuno-evasion induced inhibition inhibitors injection interactions kinase kinetics lesions leukemia LTGFb lymphoma malignant mathematical models mechanisms melanoma metastasis mice microenvironment micrometastases molecular Nat Rev Cancer Natl Acad Sci niche oncogene oncogene addiction Oncol parameters pathways phenotype potential primary tumor Proc Natl Acad proliferation protein quiescence receptor regression regulation role secondary tumor self-renewal senescence signaling simulations Springer Science+Business Media surgery survival Systems Biology T-cells target therapeutic therapy tissue treatment tumor dormancy tumor growth tumor populations tumor progression vascular vivo