The Antimicrobial DrugsOxford University Press, 2000 - 607 Seiten Deriving from Pratt's Fundamentals of Chemotherapy (OUP, 1973), Chemotherapy of Infection (OUP, 1977), and The Antimicrobial Drugs (OUP, 1986), this superb text surveys the drugs used to treat bacterial, fungal, parasitic and viral infections. It describes in comprehensive detail the mechanisms for both the antimicrobial actions and the adverse clinical effects of the these drugs. No other book provides such a thorough yet readily accessible discussion of how the body handles antibiotics. For this edition Eric Scholar has joined Dr Pratt as co-author, and the entire text has been updated. Two completely new chapters on the quinolones and antiretroviral agents have been added. With over 3500 references and numerous charts and tables summarizing each drug's pharmacokinetic properties as well as microbial susceptibility, this is an invaluable resource for graduate students in pharmacology and microbiology, medical students, pharmacy students, infectious disease specialists, clinical pharmacists, and clinicl microbiologists. |
Inhalt
Determinants of Bacterial Response to Antimicrobial Agents | 3 |
Drug Resistance | 37 |
PART 4 | 40 |
The Inhibitors of Cell Wall Synthesis I | 51 |
The Inhibitors of Cell Wall Synthesis II | 81 |
Bactericidal Inhibitors of Protein Synthesis | 127 |
Bacteriostatic Inhibitors of Protein Synthesis | 159 |
The Antimetabolites | 211 |
Drugs that Act on Mycobacteria | 280 |
PART 3 | 325 |
DRUGS EMPLOYED IN THE TREATMENT OF PARASITIC DISEASE | 373 |
Chemotherapy of Protozoal Diseases | 419 |
Chemotherapy of Helminthic Diseases | 458 |
PART 5 | 489 |
Chemotherapy of Viral Infections II | 550 |
| 587 | |
Andere Ausgaben - Alle anzeigen
Häufige Begriffe und Wortgruppen
absorption acetylators activity administration aeruginosa Agents Chemother allergic amikacin amino aminoglycosides amphotericin ampicillin anaerobic antibacterial antibiotics Antimicrob B-lactam B-lactamases bacilli bacteria bactericidal binding Biochem Biol cause cell wall cephalosporins Chem chloramphenicol chloroquine cillin ciprofloxacin Clin clindamycin clinical concentrations dosage dose drug effect Engl enzyme erythromycin Escherichia coli ethambutol excreted fluoroquinolones gastrointestinal genes gentamicin gram-negative gram-negative bacteria gram-positive growth half-life hepatic influenzae inhibition inhibitor interaction intravenous isolates isoniazid lipid liver mechanism of action membrane meningitis metabolism mutants mycin Mycobacterium nalidixic acid Neisseria nephrotoxicity nitrofurantoin occur oral organisms patients penicillin Pharmacokinetics Pharmacol pharmacology plasma plasmids pneumoniae polymyxin protein synthesis Pseudomonas quinolones reactions renal function resis resistance ribosomes rifampin sensitive serum levels spectrum Staphylococcus aureus strains Streptococcus streptomycin studies subunit sulfonamides susceptible Table tetracycline Ther therapeutic therapy tion tissue TMP-SMX tobramycin toxicity tract infections treat treatment trimethoprim tuberculosis urinary tract urine vancomycin vitro µg/ml