Cell Cycle in Development

Cover
Jacek Z. Kubiak
Springer Science & Business Media, 01.06.2011 - 588 Seiten

This book focuses on the intersection between cell cycle regulation and embryo development. Specific modifications of the canonical cell cycle occur throughout the whole period of development and are adapted to fulfil functions coded by the developmental program. Deciphering these adaptations is essential to comprehending how living organisms develop. The aim of this book is to review the best-known modifications and adaptations of the cell cycle during development. The first chapters cover the general problems of how the cell cycle evolves, while consecutive chapters guide readers through the plethora of such phenomena. The book closes with a description of specific changes in the cell cycle of neurons in the senescent human brain. Taken together, the chapters present a panorama of species - from worms to humans - and of developmental stages - from unfertilized oocyte to aged adult.

 

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Inhalt

Chapter 1 Experimental Systems to Explore Life Origin Perspectives for Understanding Primitive Mechanisms of Cell Division
1
Chapter 2 Evolution of BetHedging Mechanisms in Cell Cycle and Embryo Development Stimulated by Weak Linkage of Stochastic Processes
11
Chapter 3 Mechanics and Regulation of Cell Shape During the Cell Cycle
31
Chapter 4 The Spindle Assembly Checkpoint Clock or Domino?
74
Chapter 5 CellSizeDependent Control of Organelle Sizes During Development
93
Chapter 6 The First Cell Cycle of the Caenorhabditis elegans Embryo Spatial and Temporal Control of an Asymmetric Cell Division
109
Chapter 7 EGG Molecules Couple the OocytetoEmbryo Transition with Cell Cycle Progression
134
Chapter 8 Cell Cycle in Ascidian Eggs and Embryos
153
Chapter 14 Protein Kinases and Protein Phosphatases that Regulate Meiotic Maturation in Mouse Oocytes
309
Chapter 15 AnaphasePromoting Complex Control in Female Mouse Meiosis
342
Chapter 16 Established and Novel CdkCyclin Complexes Regulating the Cell Cycle and Development
365
Chapter 17 Function of the AType Cyclins During Gametogenesis and Early Embryogenesis
390
Chapter 18 Cell Cycle Adaptations and Maintenance of Genomic Integrity in Embryonic Stem Cells and Induced Pluripotent Stem Cells
415
Chapter 19 Cell Cycle Regulation by microRNAs in Stem Cells
459
Chapter 20 Cell Cycle Regulation During Proliferation and Differentiation of Mammalian Muscle Precursor Cells
473
Chapter 21 Drosophila Neural Stem Cells Cell Cycle Control of SelfRenewal Differentiation and Termination in Brain Development
528

Chapter 9 Regulatory Pathways Coordinating Cell Cycle Progression in Early Xenopus Development
170
Chapter 10 Control of DNA Replication by CyclinDependent Kinases in Development
201
Chapter 11 Greatwall Kinase ARPP19 and Protein Phosphatase 2A Shifting the Mitosis Paradigm
218
Chapter 12 The Role of RanGTP Gradient in Vertebrate Oocyte Maturation
235
Chapter 13 Cell Cycle Control of Germ Cell Differentiation
269
Chapter 22 Control of Neuronal Ploidy During Vertebrate Development
547
Chapter 23 Cell Cycle Deregulation in the Neurons of Alzheimers Disease
565
Index
577
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