Computational Systems Biology: From Molecular Mechanisms to DiseaseAndres Kriete, Roland Eils Academic Press, 26.11.2013 - 548 Seiten This comprehensively revised second edition of Computational Systems Biology discusses the experimental and theoretical foundations of the function of biological systems at the molecular, cellular or organismal level over temporal and spatial scales, as systems biology advances to provide clinical solutions to complex medical problems. In particular the work focuses on the engineering of biological systems and network modeling.
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Im Buch
Seite v
... Biochemical Networks of Life Through Systems Biology HANS V. WESTERHOFF, FEI HE, ETTORE MURABITO, FRÉDÉRIC CRÉMAZY, MATTEO BARBERIS 1 Principles based on topology of the genome-wide metabolic network: limited numbers of possible flux ...
... Biochemical Networks of Life Through Systems Biology HANS V. WESTERHOFF, FEI HE, ETTORE MURABITO, FRÉDÉRIC CRÉMAZY, MATTEO BARBERIS 1 Principles based on topology of the genome-wide metabolic network: limited numbers of possible flux ...
Seite 4
... biochemical networks of life through systems biology” and discusses a number of basic, more recent and upcoming discoveries of network principles. The contributors review analytical procedures from flux balance in metabolic networks to ...
... biochemical networks of life through systems biology” and discusses a number of basic, more recent and upcoming discoveries of network principles. The contributors review analytical procedures from flux balance in metabolic networks to ...
Seite 19
... biochemical networks. Curr. Opin. Struct. Biol. 17:166–172. Sunyaev, S., Ramensky, V., and Bork, P. (2000). Towards a structural basis of human non-synonymous single nucleotide polymorphisms. Trends Genet. 16:198–200. Tuncbag, N ...
... biochemical networks. Curr. Opin. Struct. Biol. 17:166–172. Sunyaev, S., Ramensky, V., and Bork, P. (2000). Towards a structural basis of human non-synonymous single nucleotide polymorphisms. Trends Genet. 16:198–200. Tuncbag, N ...
Seite 21
... Biochemical Networks of Life Through Systems Biology 1 PRINCIPLES BASED ON TOPOLOGY OF THE GENOME-WIDE METABOLIC NETWORK: http://dx.doi.org/10.1016/B978-0-12-405926-9.00003-4 Cellular communication is mediated by extracellular stimuli ...
... Biochemical Networks of Life Through Systems Biology 1 PRINCIPLES BASED ON TOPOLOGY OF THE GENOME-WIDE METABOLIC NETWORK: http://dx.doi.org/10.1016/B978-0-12-405926-9.00003-4 Cellular communication is mediated by extracellular stimuli ...
Seite 22
... biochemical networks of cell biology. The genome-wide reconstructions of enzyme-mediated metabolic activities in various organisms have led to long lists of correspondences between genes, proteins, enzyme activities, and to implied ...
... biochemical networks of cell biology. The genome-wide reconstructions of enzyme-mediated metabolic activities in various organisms have led to long lists of correspondences between genes, proteins, enzyme activities, and to implied ...
Inhalt
1 | |
9 | |
21 | |
45 | |
5 Complexities in Quantitative Systems Analysis of Signaling Networks | 65 |
Estimation Modeling and Simulation | 89 |
7 Reconstruction of Metabolic Network from Genome Information and its Structural and Functional Analysis | 113 |
8 Standards Platforms and Applications | 133 |
From Network Structure to Attractor Landscapes Landscape | 241 |
From Single Cells to Colonies | 277 |
14 Advances in Machine Learning for Processing and Comparison of Metagenomic Data | 295 |
15 Systems Biology of Infectious Diseases and Vaccines | 331 |
16 Computational Modeling and Simulation of Animal Early Embryogenesis with the MecaGen Platform | 359 |
17 Developing a Systems Biology of Aging | 407 |
18 Molecular Correlates of Morphometric Subtypes in Glioblastoma Multiforme | 423 |
Mathematical Models of Apoptosis | 455 |
9 Databases Standards and Modeling Platforms for Systems Biology | 169 |
Deterministic versus Stochastic Approaches | 183 |
11 TopDown Dynamical Modeling of Molecular Regulatory Networks | 223 |
Author Index | 483 |
Subject Index | 525 |
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Computational Systems Biology: From Molecular Mechanisms to Disease Andres Kriete,Roland Eils Keine Leseprobe verfügbar - 2013 |
Häufige Begriffe und Wortgruppen
activation algorithm analysis annotation apoptosis approach attractor Bayesian networks behavior binding biochemical Bioinformatics Biol Boolean network cancer caspase caspase-8 cell types CellML cellular circadian clock circadian oscillations circadian rhythms coefficient complex concentration corresponding cycle database described deterministic differentiation discrete domain Drosophila dynamics embryo enzyme equations experimental feedback Figure flux gene expression gene networks gene regulatory networks genetic genome Goldbeter graph identify immune integration interactions intracellular k-mers KEGG kinase kinetic Leloup ligand mammalian mathematical models mechanisms membrane metabolic network metabolites metagenomic methods microarray model for circadian modules molecular molecules mRNA network model nodes optimal organisms parameter perturbation phosphorylation predict protein proteomics quantitative reactions receptor regulation represent response robustness samples SBML sequences signal transduction signaling networks signaling pathways simulation specific stochastic structure tion tissue transcription transition vaccine variables XIAP