Computational Systems Biology: From Molecular Mechanisms to DiseaseAndres Kriete, Roland Eils Academic Press, 26.11.2013 - 548 Seiten This comprehensively revised second edition of Computational Systems Biology discusses the experimental and theoretical foundations of the function of biological systems at the molecular, cellular or organismal level over temporal and spatial scales, as systems biology advances to provide clinical solutions to complex medical problems. In particular the work focuses on the engineering of biological systems and network modeling.
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Seite 18
... transcripts and proteins. Nucleic Acids Res. 33:D501–D504. Punta, M., Coggill, P. C., Eberhardt, R. Y., Mistry, J., Tate, J., Boursnell, C., Pang, N., Forslund, K., Ceric, G., Clements, J., et al. (2012). The Pfam protein families ...
... transcripts and proteins. Nucleic Acids Res. 33:D501–D504. Punta, M., Coggill, P. C., Eberhardt, R. Y., Mistry, J., Tate, J., Boursnell, C., Pang, N., Forslund, K., Ceric, G., Clements, J., et al. (2012). The Pfam protein families ...
Seite 32
... transcription regulation, appreciating that transcription integrates the time dependence of Erk-PP, and accepting that the duration of Erk-PP signaling relative to its amplitude is important, Hornberg et al. (2005) concluded that the ...
... transcription regulation, appreciating that transcription integrates the time dependence of Erk-PP, and accepting that the duration of Erk-PP signaling relative to its amplitude is important, Hornberg et al. (2005) concluded that the ...
Seite 45
... transcription factor activity and gene expression. Cells differ in their competence to respond to extracellular stimuli. A deeper understanding of. 45. © 2014 Elsevier Inc. All rights reserved. Computational Systems Biology, Second ...
... transcription factor activity and gene expression. Cells differ in their competence to respond to extracellular stimuli. A deeper understanding of. 45. © 2014 Elsevier Inc. All rights reserved. Computational Systems Biology, Second ...
Seite 49
... transcription (RNA (ribonucleic acid) synthesis). Also the post-transcriptional processing of pre-messenger RNA such as RNA splicing occurs inside the nucleus and mature mRNAs are transported into the cytoplasm where the translational ...
... transcription (RNA (ribonucleic acid) synthesis). Also the post-transcriptional processing of pre-messenger RNA such as RNA splicing occurs inside the nucleus and mature mRNAs are transported into the cytoplasm where the translational ...
Seite 50
... transcription of target genes. The principal modes that are used for intracellular communication are: phosphorylation, second messengers, degradation, and complex formation. 2.2.1 Phosphorylation In order to convey an intracellular ...
... transcription of target genes. The principal modes that are used for intracellular communication are: phosphorylation, second messengers, degradation, and complex formation. 2.2.1 Phosphorylation In order to convey an intracellular ...
Inhalt
1 | |
9 | |
21 | |
45 | |
65 | |
89 | |
7 Reconstruction of Metabolic Network from Genome Information and its Structural and Functional Analysis | 113 |
8 Standards Platforms and Applications | 133 |
From Network Structure to Attractor Landscapes Landscape | 241 |
From Single Cells to Colonies | 277 |
14 Advances in Machine Learning for Processing and Comparison of Metagenomic Data | 295 |
15 Systems Biology of Infectious Diseases and Vaccines | 331 |
16 Computational Modeling and Simulation of Animal Early Embryogenesis with the MecaGen Platform | 359 |
17 Developing a Systems Biology of Aging | 407 |
18 Molecular Correlates of Morphometric Subtypes in Glioblastoma Multiforme | 423 |
Mathematical Models of Apoptosis | 455 |
9 Databases Standards and Modeling Platforms for Systems Biology | 169 |
Deterministic versus Stochastic Approaches | 183 |
11 TopDown Dynamical Modeling of Molecular Regulatory Networks | 223 |
Author Index | 483 |
Subject Index | 525 |
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Computational Systems Biology: From Molecular Mechanisms to Disease Andres Kriete,Roland Eils Keine Leseprobe verfügbar - 2013 |
Häufige Begriffe und Wortgruppen
activation algorithm analysis annotation apoptosis approach attractor Bayesian networks behavior binding biochemical Bioinformatics Biol Boolean network cancer caspase caspase-8 cell types CellML cellular circadian clock circadian oscillations circadian rhythms coefficient complex concentration corresponding cycle database described deterministic differentiation discrete domain Drosophila dynamics embryo enzyme equations experimental feedback Figure flux gene expression gene networks gene regulatory networks genetic genome Goldbeter graph identify immune integration interactions intracellular k-mers KEGG kinase kinetic Leloup ligand mammalian mathematical models mechanisms membrane metabolic network metabolites metagenomic methods microarray model for circadian modules molecular molecules mRNA network model nodes optimal organisms parameter perturbation phosphorylation predict protein proteomics quantitative reactions receptor regulation represent response robustness samples SBML sequences signal transduction signaling networks signaling pathways simulation specific stochastic structure tion tissue transcription transition vaccine variables XIAP