Computational Systems Biology: From Molecular Mechanisms to DiseaseAndres Kriete, Roland Eils Academic Press, 26.11.2013 - 548 Seiten This comprehensively revised second edition of Computational Systems Biology discusses the experimental and theoretical foundations of the function of biological systems at the molecular, cellular or organismal level over temporal and spatial scales, as systems biology advances to provide clinical solutions to complex medical problems. In particular the work focuses on the engineering of biological systems and network modeling.
|
Im Buch
Ergebnisse 1-5 von 92
Seite v
... specific protein sites 14 7 Current and future needs 14 8 Concluding remarks 16 9 Acknowledgments 16 References 16 3. Understanding Principles of the Dynamic Biochemical Networks of Life Through Systems Biology HANS V. WESTERHOFF, FEI ...
... specific protein sites 14 7 Current and future needs 14 8 Concluding remarks 16 9 Acknowledgments 16 References 16 3. Understanding Principles of the Dynamic Biochemical Networks of Life Through Systems Biology HANS V. WESTERHOFF, FEI ...
Seite 3
... specific diseases. In contrast, pharmaceutical companies are currently lacking criteria to select the most valuable targets, R&D expenses skyrocket, and new drugs rarely hit the market and often fail in clinical trials, while physicians ...
... specific diseases. In contrast, pharmaceutical companies are currently lacking criteria to select the most valuable targets, R&D expenses skyrocket, and new drugs rarely hit the market and often fail in clinical trials, while physicians ...
Seite 4
... specific introductions and outlooks. The first section of this book introduces essential foundations of systems biology, principles of network reconstruction based on high-throughput data with the help of engineering principles such as ...
... specific introductions and outlooks. The first section of this book introduces essential foundations of systems biology, principles of network reconstruction based on high-throughput data with the help of engineering principles such as ...
Seite 9
... specific protein sites 14 7 Current and future needs 14 8 Concluding remarks 16 References 16 Abstract The best understanding of complex biological systems ultimately comes from details of the underlying atomic structures within it. In ...
... specific protein sites 14 7 Current and future needs 14 8 Concluding remarks 16 References 16 Abstract The best understanding of complex biological systems ultimately comes from details of the underlying atomic structures within it. In ...
Seite 10
... specific atoms involved in a process. Today, thanks to more than a decade of Structural Genomics driven advances in structure determination by X-ray, NMR, and electron microscopy, there are structural representatives for almost every ...
... specific atoms involved in a process. Today, thanks to more than a decade of Structural Genomics driven advances in structure determination by X-ray, NMR, and electron microscopy, there are structural representatives for almost every ...
Inhalt
1 | |
9 | |
21 | |
45 | |
65 | |
89 | |
7 Reconstruction of Metabolic Network from Genome Information and its Structural and Functional Analysis | 113 |
8 Standards Platforms and Applications | 133 |
From Network Structure to Attractor Landscapes Landscape | 241 |
From Single Cells to Colonies | 277 |
14 Advances in Machine Learning for Processing and Comparison of Metagenomic Data | 295 |
15 Systems Biology of Infectious Diseases and Vaccines | 331 |
16 Computational Modeling and Simulation of Animal Early Embryogenesis with the MecaGen Platform | 359 |
17 Developing a Systems Biology of Aging | 407 |
18 Molecular Correlates of Morphometric Subtypes in Glioblastoma Multiforme | 423 |
Mathematical Models of Apoptosis | 455 |
9 Databases Standards and Modeling Platforms for Systems Biology | 169 |
Deterministic versus Stochastic Approaches | 183 |
11 TopDown Dynamical Modeling of Molecular Regulatory Networks | 223 |
Author Index | 483 |
Subject Index | 525 |
Andere Ausgaben - Alle anzeigen
Computational Systems Biology: From Molecular Mechanisms to Disease Andres Kriete,Roland Eils Keine Leseprobe verfügbar - 2013 |
Häufige Begriffe und Wortgruppen
activation algorithm analysis annotation apoptosis approach attractor Bayesian networks behavior binding biochemical Bioinformatics Biol Boolean network cancer caspase caspase-8 cell types CellML cellular circadian clock circadian oscillations circadian rhythms coefficient complex concentration corresponding cycle database described deterministic differentiation discrete domain Drosophila dynamics embryo enzyme equations experimental feedback Figure flux gene expression gene networks gene regulatory networks genetic genome Goldbeter graph identify immune integration interactions intracellular k-mers KEGG kinase kinetic Leloup ligand mammalian mathematical models mechanisms membrane metabolic network metabolites metagenomic methods microarray model for circadian modules molecular molecules mRNA network model nodes optimal organisms parameter perturbation phosphorylation predict protein proteomics quantitative reactions receptor regulation represent response robustness samples SBML sequences signal transduction signaling networks signaling pathways simulation specific stochastic structure tion tissue transcription transition vaccine variables XIAP