Computational Systems Biology: From Molecular Mechanisms to DiseaseAndres Kriete, Roland Eils Academic Press, 26.11.2013 - 548 Seiten This comprehensively revised second edition of Computational Systems Biology discusses the experimental and theoretical foundations of the function of biological systems at the molecular, cellular or organismal level over temporal and spatial scales, as systems biology advances to provide clinical solutions to complex medical problems. In particular the work focuses on the engineering of biological systems and network modeling.
|
Im Buch
Ergebnisse 1-5 von 47
Seite vii
... sample analysis 306 5 Understanding microbial communities 319 6 Open problems and challenges 320 Acknowledgments 321 References 322 15. Systems Biology of Infectious Diseases and Vaccines HELDER INAKAYA 1 Introduction 332 2 A brief ...
... sample analysis 306 5 Understanding microbial communities 319 6 Open problems and challenges 320 Acknowledgments 321 References 322 15. Systems Biology of Infectious Diseases and Vaccines HELDER INAKAYA 1 Introduction 332 2 A brief ...
Seite 6
... samples from different parts of the environment, reflecting the microbiome, has strongly developed in the last years and has become one of the sustained biocomputational endeavors. Identification, classification, and visualization via ...
... samples from different parts of the environment, reflecting the microbiome, has strongly developed in the last years and has become one of the sustained biocomputational endeavors. Identification, classification, and visualization via ...
Seite 61
... samples simultaneously but a method for reliable signal normalization is still under development; (2) Multiplex bead-based technology is based on microscopic beads labeled with fluorescent dye that function as solid support for ...
... samples simultaneously but a method for reliable signal normalization is still under development; (2) Multiplex bead-based technology is based on microscopic beads labeled with fluorescent dye that function as solid support for ...
Seite 62
... samples and the determination of protein abundances. Additionally, mass spectrometry can be used to measure with high accuracy the degree of phosphorylation of target proteins by using internal standards (Hahn et al. 2013); (5) Cell ...
... samples and the determination of protein abundances. Additionally, mass spectrometry can be used to measure with high accuracy the degree of phosphorylation of target proteins by using internal standards (Hahn et al. 2013); (5) Cell ...
Seite 86
... samples. FEBS Lett. 583:3966–3973. Marchisio, M. A., and Stelling, J. (2011). Automatic design of digital synthetic gene circuits. PLoS Comput. Biol. 7:e1001083. Meyers, J., Craig, J., and Odde, D. J. (2006). Potential for control of ...
... samples. FEBS Lett. 583:3966–3973. Marchisio, M. A., and Stelling, J. (2011). Automatic design of digital synthetic gene circuits. PLoS Comput. Biol. 7:e1001083. Meyers, J., Craig, J., and Odde, D. J. (2006). Potential for control of ...
Inhalt
1 | |
9 | |
21 | |
45 | |
65 | |
89 | |
7 Reconstruction of Metabolic Network from Genome Information and its Structural and Functional Analysis | 113 |
8 Standards Platforms and Applications | 133 |
From Network Structure to Attractor Landscapes Landscape | 241 |
From Single Cells to Colonies | 277 |
14 Advances in Machine Learning for Processing and Comparison of Metagenomic Data | 295 |
15 Systems Biology of Infectious Diseases and Vaccines | 331 |
16 Computational Modeling and Simulation of Animal Early Embryogenesis with the MecaGen Platform | 359 |
17 Developing a Systems Biology of Aging | 407 |
18 Molecular Correlates of Morphometric Subtypes in Glioblastoma Multiforme | 423 |
Mathematical Models of Apoptosis | 455 |
9 Databases Standards and Modeling Platforms for Systems Biology | 169 |
Deterministic versus Stochastic Approaches | 183 |
11 TopDown Dynamical Modeling of Molecular Regulatory Networks | 223 |
Author Index | 483 |
Subject Index | 525 |
Andere Ausgaben - Alle anzeigen
Computational Systems Biology: From Molecular Mechanisms to Disease Andres Kriete,Roland Eils Keine Leseprobe verfügbar - 2013 |
Häufige Begriffe und Wortgruppen
activation algorithm analysis annotation apoptosis approach attractor Bayesian networks behavior binding biochemical Bioinformatics Biol Boolean network cancer caspase caspase-8 cell types CellML cellular circadian clock circadian oscillations circadian rhythms coefficient complex concentration corresponding cycle database described deterministic differentiation discrete domain Drosophila dynamics embryo enzyme equations experimental feedback Figure flux gene expression gene networks gene regulatory networks genetic genome Goldbeter graph identify immune integration interactions intracellular k-mers KEGG kinase kinetic Leloup ligand mammalian mathematical models mechanisms membrane metabolic network metabolites metagenomic methods microarray model for circadian modules molecular molecules mRNA network model nodes optimal organisms parameter perturbation phosphorylation predict protein proteomics quantitative reactions receptor regulation represent response robustness samples SBML sequences signal transduction signaling networks signaling pathways simulation specific stochastic structure tion tissue transcription transition vaccine variables XIAP