Computational Systems Biology: From Molecular Mechanisms to DiseaseAndres Kriete, Roland Eils Academic Press, 26.11.2013 - 548 Seiten This comprehensively revised second edition of Computational Systems Biology discusses the experimental and theoretical foundations of the function of biological systems at the molecular, cellular or organismal level over temporal and spatial scales, as systems biology advances to provide clinical solutions to complex medical problems. In particular the work focuses on the engineering of biological systems and network modeling.
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Im Buch
Ergebnisse 1-5 von 63
Seite v
... metabolic network: limited numbers of possible flux patterns 22 2 Principles based on topology of the genome-wide metabolic network: toward personalized medicine 25 3 Industrially relevant applications of topology and objective-based ...
... metabolic network: limited numbers of possible flux patterns 22 2 Principles based on topology of the genome-wide metabolic network: toward personalized medicine 25 3 Industrially relevant applications of topology and objective-based ...
Seite vi
... Metabolic Network from Genome Information and its Structural and Functional Analysis HONG-WU MA, AN-PING ZENG 1 Introduction 114 2 Reconstruction of genome scale metabolic networks 114 3 Mathematical representation of metabolic networks ...
... Metabolic Network from Genome Information and its Structural and Functional Analysis HONG-WU MA, AN-PING ZENG 1 Introduction 114 2 Reconstruction of genome scale metabolic networks 114 3 Mathematical representation of metabolic networks ...
Seite 4
... metabolic pathways, signal transduction cascades, cell-cell communication ... network reconstruction based on high-throughput data with the help of ... network principles. The contributors review analytical procedures from flux balance in ...
... metabolic pathways, signal transduction cascades, cell-cell communication ... network reconstruction based on high-throughput data with the help of ... network principles. The contributors review analytical procedures from flux balance in ...
Seite 17
... metabolic thermotolerance in Escherichia coli. Science 340:1220–1223. Choudhary, C., and Mann, M. (2010). Decoding signalling networks by mass spectrometry-based proteomics. Nat. Rev. Mol. Cell Biol. 11:427–439. Croft, D., O'Kelly, G ...
... metabolic thermotolerance in Escherichia coli. Science 340:1220–1223. Choudhary, C., and Mann, M. (2010). Decoding signalling networks by mass spectrometry-based proteomics. Nat. Rev. Mol. Cell Biol. 11:427–439. Croft, D., O'Kelly, G ...
Seite 19
... networks. Curr. Opin. Struct. Biol. 17:166–172. Sunyaev, S., Ramensky, V., and Bork, P. (2000). Towards a structural basis ... metabolic network of Thermotoga maritima. Science 325:1544–1549. This page is intentionally left blank C H A P ...
... networks. Curr. Opin. Struct. Biol. 17:166–172. Sunyaev, S., Ramensky, V., and Bork, P. (2000). Towards a structural basis ... metabolic network of Thermotoga maritima. Science 325:1544–1549. This page is intentionally left blank C H A P ...
Inhalt
1 | |
9 | |
21 | |
45 | |
65 | |
89 | |
7 Reconstruction of Metabolic Network from Genome Information and its Structural and Functional Analysis | 113 |
8 Standards Platforms and Applications | 133 |
From Network Structure to Attractor Landscapes Landscape | 241 |
From Single Cells to Colonies | 277 |
14 Advances in Machine Learning for Processing and Comparison of Metagenomic Data | 295 |
15 Systems Biology of Infectious Diseases and Vaccines | 331 |
16 Computational Modeling and Simulation of Animal Early Embryogenesis with the MecaGen Platform | 359 |
17 Developing a Systems Biology of Aging | 407 |
18 Molecular Correlates of Morphometric Subtypes in Glioblastoma Multiforme | 423 |
Mathematical Models of Apoptosis | 455 |
9 Databases Standards and Modeling Platforms for Systems Biology | 169 |
Deterministic versus Stochastic Approaches | 183 |
11 TopDown Dynamical Modeling of Molecular Regulatory Networks | 223 |
Author Index | 483 |
Subject Index | 525 |
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Computational Systems Biology: From Molecular Mechanisms to Disease Andres Kriete,Roland Eils Keine Leseprobe verfügbar - 2013 |
Häufige Begriffe und Wortgruppen
activation algorithm analysis annotation apoptosis approach attractor Bayesian networks behavior binding biochemical Bioinformatics Biol Boolean network cancer caspase caspase-8 cell types CellML cellular circadian clock circadian oscillations circadian rhythms coefficient complex concentration corresponding cycle database described deterministic differentiation discrete domain Drosophila dynamics embryo enzyme equations experimental feedback Figure flux gene expression gene networks gene regulatory networks genetic genome Goldbeter graph identify immune integration interactions intracellular k-mers KEGG kinase kinetic Leloup ligand mammalian mathematical models mechanisms membrane metabolic network metabolites metagenomic methods microarray model for circadian modules molecular molecules mRNA network model nodes optimal organisms parameter perturbation phosphorylation predict protein proteomics quantitative reactions receptor regulation represent response robustness samples SBML sequences signal transduction signaling networks signaling pathways simulation specific stochastic structure tion tissue transcription transition vaccine variables XIAP