Computational Systems Biology: From Molecular Mechanisms to DiseaseAndres Kriete, Roland Eils Academic Press, 26.11.2013 - 548 Seiten This comprehensively revised second edition of Computational Systems Biology discusses the experimental and theoretical foundations of the function of biological systems at the molecular, cellular or organismal level over temporal and spatial scales, as systems biology advances to provide clinical solutions to complex medical problems. In particular the work focuses on the engineering of biological systems and network modeling.
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Im Buch
Ergebnisse 1-5 von 85
Seite 1
... behavior analysis (Kitano 2001). In molecular biology, system identification amounts to identifying the regulatory relationships between genes, proteins, and small molecules, as well as their inherent dynamics hidden in the specific ...
... behavior analysis (Kitano 2001). In molecular biology, system identification amounts to identifying the regulatory relationships between genes, proteins, and small molecules, as well as their inherent dynamics hidden in the specific ...
Seite 2
... behavior. The constitutive model parameters may be measured directly or may be inferred during this validation process, however, the propagation of errors through these parameters present significant challenges for the modeler. If data ...
... behavior. The constitutive model parameters may be measured directly or may be inferred during this validation process, however, the propagation of errors through these parameters present significant challenges for the modeler. If data ...
Seite 4
... behavior. Such biosimulation concepts will continue to transform current diagnostic and therapeutic approaches to medicine. 2. OVERVIEW. OF. THE. CONTENT. This completely revised, second edition of this book presents examples selected from ...
... behavior. Such biosimulation concepts will continue to transform current diagnostic and therapeutic approaches to medicine. 2. OVERVIEW. OF. THE. CONTENT. This completely revised, second edition of this book presents examples selected from ...
Seite 5
... behaviors in biological systems. “Computational models for circadian rhythms - deterministic versus stochastic ... behavior and how several results can be obtained in models which possess a minimum degree of complexity. Circadian ...
... behaviors in biological systems. “Computational models for circadian rhythms - deterministic versus stochastic ... behavior and how several results can be obtained in models which possess a minimum degree of complexity. Circadian ...
Seite 6
... behavior to tissue deformation: computational modeling and simulation of early animal embryogenesis,” Chapter 16. They propose a theoretical, yet realistic agent-based model and simulation platform of animal embryogenesis, to study the ...
... behavior to tissue deformation: computational modeling and simulation of early animal embryogenesis,” Chapter 16. They propose a theoretical, yet realistic agent-based model and simulation platform of animal embryogenesis, to study the ...
Inhalt
1 | |
9 | |
21 | |
45 | |
65 | |
89 | |
7 Reconstruction of Metabolic Network from Genome Information and its Structural and Functional Analysis | 113 |
8 Standards Platforms and Applications | 133 |
From Network Structure to Attractor Landscapes Landscape | 241 |
From Single Cells to Colonies | 277 |
14 Advances in Machine Learning for Processing and Comparison of Metagenomic Data | 295 |
15 Systems Biology of Infectious Diseases and Vaccines | 331 |
16 Computational Modeling and Simulation of Animal Early Embryogenesis with the MecaGen Platform | 359 |
17 Developing a Systems Biology of Aging | 407 |
18 Molecular Correlates of Morphometric Subtypes in Glioblastoma Multiforme | 423 |
Mathematical Models of Apoptosis | 455 |
9 Databases Standards and Modeling Platforms for Systems Biology | 169 |
Deterministic versus Stochastic Approaches | 183 |
11 TopDown Dynamical Modeling of Molecular Regulatory Networks | 223 |
Author Index | 483 |
Subject Index | 525 |
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Computational Systems Biology: From Molecular Mechanisms to Disease Andres Kriete,Roland Eils Keine Leseprobe verfügbar - 2013 |
Häufige Begriffe und Wortgruppen
activation algorithm analysis annotation apoptosis approach attractor Bayesian networks behavior binding biochemical Bioinformatics Biol Boolean network cancer caspase caspase-8 cell types CellML cellular circadian clock circadian oscillations circadian rhythms coefficient complex concentration corresponding cycle database described deterministic differentiation discrete domain Drosophila dynamics embryo enzyme equations experimental feedback Figure flux gene expression gene networks gene regulatory networks genetic genome Goldbeter graph identify immune integration interactions intracellular k-mers KEGG kinase kinetic Leloup ligand mammalian mathematical models mechanisms membrane metabolic network metabolites metagenomic methods microarray model for circadian modules molecular molecules mRNA network model nodes optimal organisms parameter perturbation phosphorylation predict protein proteomics quantitative reactions receptor regulation represent response robustness samples SBML sequences signal transduction signaling networks signaling pathways simulation specific stochastic structure tion tissue transcription transition vaccine variables XIAP