Systems Biology of TuberculosisJohnjoe McFadden, Dany J.V. Beste, Andrzej M. Kierzek Springer Science & Business Media, 09.12.2012 - 228 Seiten The book starts with a general introduction into the relevance of systems biology for understanding tuberculosis. This will be followed by several chapters which describe the application of systems biology to various aspects of the study of the pathogen, Mycobacterium tuberculosis, and its interaction with the host. The book provides the reader with an account of how the new science of systems biology is providing novel insights into the ancient scourge of tuberculosis. It will also describe how systems biology can be applied to the control of tuberculosis, including the development of new treatments, vaccines and diagnostics. |
Was andere dazu sagen - Rezension schreiben
Es wurden keine Rezensionen gefunden.
Inhalt
Chapter 1 Modeling Mycobacterium tuberculosis H37Rv In Silico | 1 |
Chapter 2 Software Platform for Metabolic Network Reconstruction of Mycobacterium tuberculosis | 21 |
Chapter 3 Probing Gene Regulatory Networks to Decipher HostPathogen Interactions | 37 |
Chapter 4 Metabolism of Mycobacterium tuberculosis | 55 |
Chapter 5 ProteinProtein Interaction in the Omics Era Understanding Mycobacterium tuberculosis Function | 79 |
Chapter 6 HostPathogen Interactions | 107 |
Chapter 7 A Systems Biology Approach for Understanding Granuloma Formation and Function in Tuberculosis | 127 |
Chapter 8 Stochastic Gene Expression in Bacterial Pathogens A Mechanism for Persistence? | 157 |
Chapter 9 Drug Discovery | 179 |
Chapter 10 Immunological Biomarkers for Tuberculosis Potential for a Combinatorial Approach | 193 |
| 221 | |
Andere Ausgaben - Alle anzeigen
Systems Biology of Tuberculosis Johnjoe McFadden,Dany J.V. Beste,Andrzej M. Kierzek Keine Leseprobe verfügbar - 2015 |
Systems Biology of Tuberculosis Johnjoe McFadden,Dany J.V. Beste,Andrzej M. Kierzek Keine Leseprobe verfügbar - 2012 |
Häufige Begriffe und Wortgruppen
Acad Sci USA acid active TB alveolar macrophage analysis antibiotic antibody antigen approach bacilli bacterial biomarker biomass cellular chemokines coli complex curation cytokine databases disease drug discovery drug targets dynamics effector enzyme Escherichia coli essential experimental expression data flux Flux balance analysis function gene expression profiles gene regulatory networks genetic genome genome-wide granuloma granuloma formation growth high-throughput human identified IFNg immune response Immunol integrated interaction network intracellular large number latent LTBI lung macrophages McFadden mechanisms metabolic network metabolites metabolomics Mol Microbiol molecular molecules mutants Mycobacterium tuberculosis infection mycolic acid Natl Acad Sci noise Palsson BO parameters pathogen pathways persistence phagosome phenotypic PLoS PLoS Pathog predicted Proc Natl Acad protein protein interaction protein-protein interactions proteome reaction receptor reconstructions regulation regulatory networks regulatory T cells role signaling silico simulation stochastic studies systems biology tion transcriptome virulence vitro vivo Y2H system
Bibliografische Informationen
| Titel | Systems Biology of Tuberculosis SpringerLink : Bücher |
| Herausgeber | Johnjoe McFadden, Dany J.V. Beste, Andrzej M. Kierzek |
| Ausgabe | illustriert |
| Verlag | Springer Science & Business Media, 2012 |
| ISBN | 1461449669, 9781461449669 |
| Länge | 228 Seiten |
| Zitat exportieren | BiBTeX EndNote RefMan |