Biomolecular Networks: Methods and Applications in Systems Biology
Alternative techniques and tools for analyzing biomolecularnetworks
With the recent rapid advances in molecular biology,high-throughput experimental methods have resulted in enormousamounts of data that can be used to study biomolecular networks inliving organisms. With this development has come recognition of thefact that a complicated living organism cannot be fully understoodby merely analyzing individual components. Rather, it is theinteractions of components or biomolecular networks that areultimately responsible for an organism's form and function. Thisbook addresses the important need for a new set of computationaltools to reveal essential biological mechanisms from a systemsbiology approach.
Readers will get comprehensive coverage of analyzingbiomolecular networks in cellular systems based on availableexperimental data with an emphasis on the aspects of network,system, integration, and engineering. Each topic is treated indepth with specific biological problems and novel computationalmethods:
In addition to theoretical results and methods, manycomputational software tools are referenced and available from theauthors' Web sites. Biomolecular Networks is an indispensablereference for researchers and graduate students in bioinformatics,computational biology, systems biology, computer science, andapplied mathematics.