Multiscale Modeling of Developmental Systems

Cover
Academic Press, 18.12.2007 - 604 Seiten
Mathematical and computational biology is playing an increasingly important role in the biological sciences. This science brings forward unique challenges, many of which are, at the moment, beyond the theoretical techniques available. Developmental biology, due to its complexity, has lagged somewhat behind its sister disciplines (such as molecular biology and population biology) in making use of quantitative modeling to further biological understanding. This volume comprises work that is among the best developmental modeling available and we feel it will do much to remedy this situation.This book is aimed at all those with an interest in the interdisciplinary field of computer and mathematical modeling of multi-cellular and developmental systems. It is also a goal of the Editors to attract more developmental biologists to consider integrating modeling components into their research. Most importantly, this book is intended to serve as a portal into this research area for younger scientists – especially graduate students and post-docs, from both biological and quantitative backgrounds. - Articles written by leading exponents in the field - Provides techniques to address multiscale modeling - Coverage includes a wide spectrum of modeling approaches - Includes descriptions of the most recent advances in the field
 

Inhalt

From Elementary Steps to the Organization of Embryonic Axes
1
Chapter 2 Robustness of Embryonic Spatial Patterning in Drosophila melanogaster
65
Chapter 3 Integrating Morphogenesis with Underlying Mechanics and Cell Biology
113
Chapter 4 The Mechanisms Underlying Primitive Streak Formation in the Chick Embryo
135
Chapter 5 GridFree Models of Multicellular Systems with an Application to LargeScale Vortices Accompanying Primitive Streak Formation
157
Chapter 6 Mathematical Models for Somite Formation
183
Chapter 7 Coordinated Action of NCAM Ncadherin EphA4 and ephrinB2 Translates Genetic Prepatterns into Structure during Somitogenesis in Chick
205
Mechanics of Morphogenesis by Multiple Mechanisms
249
Chapter 12 Tooth Morphogenesis in vivo in vitro and in silico
341
Cell Mechanics with a 3D Kinetic and Dynamic Weighted DelaunayTriangulation
373
Chapter 14 Cellular Automata as Microscopic Models of Cell Migration in Heterogeneous Environments
401
Chapter 15 Multiscale Modeling of Biological Pattern Formation
435
Chapter 16 Relating Biophysical Properties Across Scales
461
New Paradigms Looking for a Mathematical Theory
485
Index
503
Contents of Previous Volumes
515

Chapter 9 Multicellular Sprouting during Vasculogenesis
269
Chapter 10 Modeling Lung Branching Morphogenesis
291
Chapter 11 Multiscale Models for Vertebrate Limb Development
311
Color Insert
541
Urheberrecht

Andere Ausgaben - Alle anzeigen

Häufige Begriffe und Wortgruppen

Bibliografische Informationen