Cell Growth and Oncogenesis
Rapid progress has been made in our understanding of the molecular mechanisms of cell growth and oncogenesis during the past decade. This book comprises recent results on the regulation of cell growth in normal and neoplastic tissues by growth factors including hormones, and by the activation and inactivation of oncogenes and tumor suppressor genes, respectively. Special attention has been given to the presentation of the frequently neglected close correlation between changes in signal transduction and metabolism pathways during oncogenesis.
Was andere dazu sagen - Rezension schreiben
Es wurden keine Rezensionen gefunden.
Andere Ausgaben - Alle anzeigen
3T3 cells a-tocopherol acid activity altered appears associated Bannasch Bari binding Biochem Biol Chem bombesin Cancer Cancer Res Carcinogenesis carcinoma cell lines cell proliferation cellular changes chromatography complex containing cycle cytoplasmic demonstrated determined DNA synthesis domain effects enzyme et al experiments expression Figure foci function gene glucose glycogen growth factor hepatic hepatocellular hepatocytes hepatoma hexokinase human important increased indicated induced inhibition initiated interaction involved islet isolated Italy known leading lesions levels lipid liver mechanisms membrane mitochondrial mitogenic molecular mRNA normal observed Oncogene P-glycoprotein pathways phenotype platelet-derived growth factor preneoplastic presence promoter protein kinase pyruvate kinase recently receptor regeneration region regulation reported resistance response role Rozengurt sequence shown signal specific stimulation studies substrate subunit suggest tissue transcription transformation transplantation tumor tyrosine phosphorylation University