Practical Systems Biology, Band 61

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Alistair Hetherington, Claire Grierson
Garland Science, 01.06.2008 - 300 Seiten
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Systems biology is the study of organisms as interacting networks of genes, proteins and reactions. Practical Systems Biology provides a detailed overview of the different approaches used in this relatively new discipline, integrating bioinformatics, genomics, proteomics and metabolomics. Various areas of research are also discussed, including the use of computational models of biological processes, and post-genomic research.

Each chapter is written by an experienced researcher and gives an excellent account of various issues of systems biology that is suitable for postgraduate and postdoctoral researchers who are interested in this expanding area of science.

 

 

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Inhalt

Cell sampling and global nucleic acid amplification
17
Challenges and opportunities
37
From DNA to flux and back
65
Using mathematical models to probe dynamic expression data
93
A dynamic and integrative
113
Spatiotemporal dynamics of protein modification cascades
141
Intracellular signalling during bacterial chemotaxis
161
Modelling the mammalian heart
175
Modelling root growth and development
195
Index
213
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