Practical Systems Biology, Band 61Systems biology is the study of organisms as interacting networks of genes, proteins and reactions. Practical Systems Biology provides a detailed overview of the different approaches used in this relatively new discipline, integrating bioinformatics, genomics, proteomics and metabolomics. Various areas of research are also discussed, including the use of computational models of biological processes, and post-genomic research. Each chapter is written by an experienced researcher and gives an excellent account of various issues of systems biology that is suitable for postgraduate and postdoctoral researchers who are interested in this expanding area of science.
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Inhalt
Cell sampling and global nucleic acid amplification | 17 |
Challenges and opportunities | 37 |
From DNA to flux and back | 65 |
Using mathematical models to probe dynamic expression data | 93 |
A dynamic and integrative | 113 |
Spatiotemporal dynamics of protein modification cascades | 141 |
Intracellular signalling during bacterial chemotaxis | 161 |
Modelling the mammalian heart | 175 |
Modelling root growth and development | 195 |
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Andere Ausgaben - Alle anzeigen
Practical Systems Biology, Band 61 Alistair Hetherington,Claire Grierson Eingeschränkte Leseprobe - 2008 |
Practical Systems Biology, Band 61 Alistair Hetherington,Claire Grierson Eingeschränkte Leseprobe - 2008 |
Practical Systems Biology, Band 61 Alistair Hetherington,Claire Grierson Keine Leseprobe verfügbar - 2008 |
Häufige Begriffe und Wortgruppen
acid action potential activity analysis approach Arabidopsis auxin bacterial chemotaxis behaviour biochemical bioinformatics Ca2+ cardiac cascade cDNA Cell Biol cellular CheA chemotaxis CheY CheYP coli complex computational concentration cycle cytoplasm database diffusion dynamics efflux carriers encoding enzyme Epistasis equations example expression data feedback Figure flux function gene expression Gene regulatory network genetic genome Hes1 hierarchical regulation Histone H4 inference interactions intracellular Kholodenko kinase labelling linear log ratios mass spectrometry mathematical models mechanisms membrane metabolic regulation methods microarray data modification modules molecular molecules mRNA mRNA amplification Natl Acad network components organisms oscillations parameters pathway patterns peptides phenotypes phosphorylation phyllotaxis Proc profiles protein Proteomics receptor regulation coefficient regulatory networks robustness root samples sequence signal transduction signalling simulation spatial specific structure studies synthesis systems biology tandem mass target time-course tion tissue transcription factor ventricular Westerhoff yeast