Handbook of Statistical Systems BiologySystems Biology is now entering a mature phase in which the key issues are characterising uncertainty and stochastic effects in mathematical models of biological systems. The area is moving towards a full statistical analysis and probabilistic reasoning over the inferences that can be made from mathematical models. This handbook presents a comprehensive guide to the discipline for practitioners and educators, in providing a full and detailed treatment of these important and emerging subjects. Leading experts in systems biology and statistics have come together to provide insight in to the major ideas in the field, and in particular methods of specifying and fitting models, and estimating the unknown parameters. This book:
This handbook will be a key resource for researchers practising systems biology, and those requiring a comprehensive overview of this important field. |
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Inhalt
Bayesian Inference and Computation | |
Data Integration Towards Understanding | |
Control Engineering Approaches toReverse Engineering Biomolecular Networks | |
Transcriptomic Technologies and Statistical Data | |
StatisticalData Analysis inMetabolomics 8 1 Introduction | |
ImagingandSingleCell Measurement | |
Chapter | |
References | |
Stochastic Dynamical Systems | |
Gaussian Process Inferencefor Differential Equation Models of Transcriptional Regulation | |
Model Identification by Utilizing Likelihood | |
1ODE Models forReaction Networks 20 2 Parameter Estimation | |
Acknowledgements | |
Inferenceand ModelSelectionforDynamical | |
References | |
Introduction to Graphical Modelling | |
Recovering Genetic Network from Continuous | |
Advanced Applications of Bayesian Networks | |
RandomGraphModels | |
3PPI network models 14 4Rangedependent graphs | |
Chapter | |
Chapter | |
HostPathogen Systems Biology | |
Bayesian Approaches for Based Metabolomics Mass Spectrometry | |
Systems Biologyof microRNAs 25 1 Introduction | |
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Handbook of Statistical Systems Biology Michael Stumpf,David J. Balding,Mark Girolami Keine Leseprobe verfügbar - 2011 |
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