Yersinia: Systems Biology and Control

Cover
Elisabeth Carniel, Bernard Joseph Hinnebusch
Horizon Scientific Press, 2012 - 245 Seiten
0 Rezensionen
Three members of the genus Yersinia are important human pathogens, causing diseases ranging from the deadly Plague (Yersinia pestis) to a relatively mild gastroenteritis (Y. enterocolitica and Y. pseudotuberculosis). Plague, a re-emerging disease, is endemic in many parts of the world. The extraordinary pathogenicity of Y. pestis makes it a potential bioterrorist weapon. On the other hand, the two enteropathogenic Yersinia species represent the third most common bacterial cause of gastroenteritis in Europe and probably elsewhere, although their prevalence is largely underestimated. This, and the emergence of antibiotic resistant Y. pestis in recent years, highlights the urgency to understand the mechanisms of pathogenicity and the need to devise new strategies for the prevention and control of human pathogenic Yersinia. In this book, leading Yersinia researchers review the hot topics in the systems biology and the control of these important bacteria. Topics include: transcriptome analysis of the bacterial response to the host, and of the host response, to a Yersinia infection * proteome analysis of the bacterial and host responses * treatment and antibiotic resistance * vaccines * surveillance * control. The book will be essential reading for everyone working on Yersinia and related organisms. It is recommended reading for researchers interested in biodefense, microbial genomics, and the evolution of microbial virulence.
 

Was andere dazu sagen - Rezension schreiben

Es wurden keine Rezensionen gefunden.

Inhalt

Yersinia pseudotuberculosis Gene Expression in Plasma
19
Host Transcriptome Responses to Yersinia pestis Infection
43
Transcriptional Profiling of Yersinia enterocoliticaHost Cell Interactions
59
Yersinia pestis Metabolic Network
83
Plague Treatment and Resistance to Antimicrobial Agents
109
Acellular Vaccines Against Plague
123
Live Vaccines Against Plague and Pseudotuberculosis
143
North American Plague Models of Enzootic Maintenance
169
Surveillance and Control of Plague
183
Tracing of Enteropathogenic Yersinia
201
Surveillance and Control of Enteric Yersinioses
217
Index
239
Urheberrecht

Häufige Begriffe und Wortgruppen

Bibliografische Informationen