Metabolome Analyses:: Strategies for Systems BiologySeetharaman Vaidyanathan, George G. Harrigan, Royston Goodacre Springer Science & Business Media, 28.04.2005 - 390 Seiten Metabolome analysis is now recognized as a crucial component of functional genomic and systems biology investigations. Innovative approaches to the study of metabolic regulation in microbial, plant and animal systems are increasingly facilitating the emergence of systems approaches in biology. This book highlights analytical and bioinformatics strategies now available for investigating metabolic networks in microbial, plant and animal systems. The contributing authors are world leaders in this field and they present an unambiguous case for pursuing metabolome analysis as a means to attain a systems level understanding of complex biological systems. |
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Inhalt
INTRODUCTION | 1 |
TOWARDS INTEGRATIVE FUNCTIONAL GENOMICS USING YEAST AS A REFERENCE MODEL | 9 |
METABOLOMICS FOR THE ASSESSMENT OF FUNCTIONAL DIVERSITY AND QUALITY TRAITS IN PLANTS | 31 |
METABOLOMICS A NEW APPROACH TOWARDS IDENTIFYING BIOMARKERS AND THERAPEUTIC TARGETS IN CNS DISORDERS | 45 |
COMPARATIVE METABOLOME PROFILING USING TWO DIMENSIONAL THIN LAYER CHROMATOGRAPHY 2DTLC | 63 |
CAPILLARY ELECTROPHORESIS AND ITS APPLICATION IN METABOLOME ANALYSIS | 83 |
METABOLITE PROFILING WITH GCMS AND LCMS | 103 |
THE APPLICATION OF ELECTROCHEMISTRY TO METABOLIC PROFILING | 119 |
DETAILED KINETIC MODELS USING METABOLOMICS DATA SETS | 215 |
METABOLIC NETWORKS | 243 |
METABOLIC NETWORKS FROM A SYSTEMS PERSPECTIVE | 265 |
PARALLEL METABOLITE AND TRANSCRIPT PROFILING | 291 |
FLUXOME PROFILING IN MICROBES | 307 |
TARGETED DRUG DESIGN AND METABOLIC PATHWAY FLUX | 323 |
METABONOMICS IN THE PHARMACEUTICAL INDUSTRY | 337 |
HOW LIPIDOMIC APPROACHES WILL BENEFIT THE PHARMACEUTICAL INDUSTRY | 349 |
DIFFERENTIAL METABOLIC PROFILING FOR BIOMARKER DISCOVERY | 137 |
NMRBASED METABONOMICS IN TOXICOLOGY RESEARCH | 159 |
METHODOLOGICAL ISSUES AND EXPERIMENTAL DESIGN CONSIDERATIONS IN METABOLIC PROFILEBASED CLASSIFICATIONS | 173 |
MODELLING OF FUNGAL METABOLISM | 195 |
METABOLITES AND FUNGAL VIRULENCE | 367 |
| 383 | |
Andere Ausgaben - Alle anzeigen
Metabolome Analyses:: Strategies for Systems Biology Seetharaman Vaidyanathan,George G. Harrigan,Royston Goodacre Eingeschränkte Leseprobe - 2006 |
Metabolome Analyses:: Strategies for Systems Biology Seetharaman Vaidyanathan,George G. Harrigan,Royston Goodacre Keine Leseprobe verfügbar - 2010 |
Häufige Begriffe und Wortgruppen
acid activity addition Anal analysis analytical application approach associated biochemical Biol biological biomarkers Biotechnol capillary cell changes Chapter Chem chromatography clustering coli combined compared complex components compounds concentrations correlation defined described detection determined direct disease drug dynamic effects enzyme et al example experimental expression extraction factors Fiehn Figure flux function gene genetic genomics given glucose groups growth human identify important increased individual integrated involved kinetic levels limited lipids markers mass mass spectrometry measurements mechanisms metabolic networks metabolic profiling metabolites metabolome methods models Nature observed obtained organisms pathways pattern peak plant possible potential production protein proteomics quantitative range rats reactions recent regulation represent response role samples sensitivity separation shows silico specific spectroscopy strains strategies structure studies techniques tool toxicity transcript understanding urine validation variables
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Risk Assessment for Environmental Health Mark G. Robson,William A. Toscano Eingeschränkte Leseprobe - 2007 |
Bibliografische Informationen
| Titel | Metabolome Analyses:: Strategies for Systems Biology [ProQuest Ebook Central] [Springer ebooks] |
| Herausgeber | Seetharaman Vaidyanathan, George G. Harrigan, Royston Goodacre |
| Ausgabe | illustriert |
| Verlag | Springer Science & Business Media, 2005 |
| ISBN | 0387252398, 9780387252391 |
| Länge | 390 Seiten |
| Zitat exportieren | BiBTeX EndNote RefMan |