Systems Biology in Cancer Research and Drug DiscoveryAsfar S Azmi Springer Science & Business Media, 29.09.2012 - 423 Seiten Systems Biology in Cancer Research and Drug Discovery provides a unique collection of chapters, by world-class researchers, describing the use of integrated systems biology and network modeling in the cancer field where traditional tools have failed to deliver expected promise. This book touches four applications/aspects of systems biology (i) in understanding aberrant signaling in cancer (ii) in identifying biomarkers and prognostic markers especially focused on angiogenesis pathways (iii) in unwinding microRNAs complexity and (iv) in anticancer drug discovery and in clinical trial design. This book reviews the state-of-the-art knowledge and touches upon cutting edge newer and improved applications especially in the area of network modeling. It is aimed at an audience ranging from students, academics, basic researcher and clinicians in cancer research. This book is expected to benefit the field of translational cancer medicine by bridging the gap between basic researchers, computational biologists and clinicians who have one ultimate goal and that is to defeat cancer. |
Im Buch
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... chapter. Finally, I would like to thank Dr. Irfana Muqbil for her unending and unconditional support in all my research endeavors. Part I Systems Biology in Cancer 1 Systems Biology Approach ix. Acknowledgment. Acknowledgment.
... Approach to Study Cancer Related Pathways.......... Yike Guo and Xian Yang 3 Modeling Oncogenic Signaling Networks ... Approach to the Study of Pancreatic Cancer ...
Asfar S Azmi. 8 Understanding the Dynamics of Tumor Angiogenesis: A Systems Biology Approach ... Approaches to Understand miRNA-mRNA Interactome in Cancer Research................................ 267 Xiaohong Li, Carolyn M. Klinge, and ...
Asfar S Azmi. Systems. Biology. Approach. to. Metabolomics. in. Cancer. Studies. Mariano Bizzarri, Simona Dinicola, and Cesare Manetti Contents 1 4 5 6 7 8 9 Why Are Metabolomics Studies so Relevant for ... Approach to Metabolomics in Cancer ...
Asfar S Azmi. in molecular biology achieved thereafter, has left no room for approaches that are anything but gene-based. Hence, the “metabolic theory” was thought as a not specific (and not ... Approach to Metabolomics in Cancer Studies.
Inhalt
Systems Approaches to Understand Cancer Progression | 165 |
Systems and Network Biology in Decoding miRNA Complexity | 246 |
Network Modeling in Cancer Drug Discovery and Clinical Trials | 307 |
Erratum | 418 |
Index | 419 |