Natural Products Chemistry, Band 3

absolute configuration Acad acetate acetyl acid Acta aldehyde alkaloids Antibiot bacteriorhodopsin Batrachotoxin Biochem Biochemistry Biol Biophys biosynthesis Bull carbon carbonyl CH2OH Chem chemical Chim chiral chromophore cleavage Columbia University Commun compounds COOH COOMe cyclization decoupling Department of Chemistry derivative determined by x-ray diastereomer double bond E.J. Corey epimer epoxide ester ether EtOH formation gave H-nmr hydrogen hydrolysis hydroxyl ibid incorporation intermediate intramolecular ir(KBr isolated isomer isomerization Jones oxidation ketone lactone Lett leukotriene leukotriene C4 methyl methyl group methylene mixture moiety molecular Nakanishi NaOH Natl Natural Products obtained OCH2Ph OH OH oxidation pathway Pharm Phytochemistry pigments precursor Proc Products Chemistry protein proton reaction reagent rearrangement reduction Remarks rhodopsin ring Route sesquiterpenes shift shown side chain signals skeleton spectral spectroscopy spectrum stereochemistry stereoselective steroid Streptomyces STRUCTURE AND SYNTHESIS Tetr Tetrahedron total synthesis Umezawa x-ray analysis yield