The advent of genome sequencing and associated technologies has transformed biologists' ability to measure important classes of molecules and their interactions. This expanded cellular view has opened the field to thousands of interactions that previously were outside the researchers' reach. The processing and interpretation of these new vast quantities of interconnected data call for sophisticated mathematical models and computational methods. Systems biology meets this need by combining genomic knowledge with theoretical, experimental and computational approaches from a number of traditional scientific disciplines to create a mechanistic explanation of cellular systems and processes. Systems Biology I: Genomics and Systems Biology II: Networks, Models, and Applications offer a much-needed study of genomic principles and their associated networks and models. Written for a wide audience, each volume presents a timely compendium of essential information that is necessary for a comprehensive study of the subject. The chapters in the two volumes reflect the hierarchical nature of systems biology. Chapter authors-world-recognized experts in their fields-provide authoritative discussions on a wide range of topics along this hierarchy. Volume I explores issues pertaining to genomics that range from prebiotic chemistry to noncoding RNAs. Volume II covers an equally wide spectrum, from mass spectrometry to embryonic stem cells. The two volumes are meant to provide a reliable reference for students and researchers alike.
Was andere dazu sagen - Rezension schreiben
Es wurden keine Rezensionen gefunden.
1 Prebiotic Chemistry on the Primitive Earth
Is a SystemLevel Understanding Feasible?
3 Shotgun Fragment Assembly
4 Gene Finding
5 Local Sequence Similarities
Reading and Comprehension
Andere Ausgaben - Alle anzeigen
active affinity algorithm alignment amino acids analysis approach assembly atmosphere binding biochemical Biology called cells common compared complex compounds computational contain database defined detection determined distance DNA sequence early Earth edges energy error et al eukaryotic evidence evolution example experimental figure finding fragment function gene genetic genome given graph human identify important improved interactions intervals involved Journal of Molecular k-mer known length matrix methods models Molecular Molecular Biology molecules multiple Nature networks Nucleic Acids Research occur organic origin overlap pair pattern position possible prebiotic prediction present primitive probability problem Proceedings processes produced protein reaction reasonable recent reducing regions regulatory relative repeat represent Research Science score short shown signals significant similar single solution specificity structure synthesis target sequence template tion transcription unique unitig