Intravoxel Incoherent Motion (IVIM) MRI: Principles and Applications

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Denis Le Bihan, Mami Iima, Christian Federau, Eric E. Sigmund
CRC Press, 05.11.2018 - 562 Seiten

Intravoxel incoherent motion (IVIM) refers to translational movements which within a given voxel and during the measurement time present a distribution of speeds in orientation and/or amplitude. The concept was introduced in 1986 together with the foundation of diffusion MRI because it had been realized that flow of blood in capillaries (perfusion) would mimic a diffusion process and impact diffusion MRI measurements. IVIM-based perfusion MRI, which does not require injection of any tracer or contrast agent, has been first investigated in the brain, but is now experiencing a remarkable revival for applications throughout the body, especially for oncologic applications, from diagnosis to treatment monitoring.

This book addresses a number of highly topical aspects of the field from leading authorities, introducing the concepts behind IVIM MRI, outlining related methodological issues, and summarizing its current usage and potential for clinical applications. It also presents future research directions, both in terms of methodological development and clinical application fields, extending to new, non-perfusion applications of IVIM MRI, such as virtual MR elastography.

 

Inhalt

Chapter 1 Introduction to IVIM MRI Denis Le Bihan
3
Section II Other MRI Approaches toPerfusion Imaging
29
Chapter 2 Other MRI Approaches to Perfusion Imaging ASL DSC DCE Emmanuel L Barbier Sylvie Grand Alexandre Krainik and Jan M Warnking
31
Neurological Applications
67
Chapter 3 Clinical Applications of IVIM MRI to the Nervous System C Federau
69
A Window to the Pathophysiology Underlying Cerebral Small Vessel Disease Jacobus F A Jansen Sau May Wong and Walter H Backes
85
Brain Activation with a High Spatial Specificity and Resolution Allen W Song Iain Bruce Christopher Petty and NanKuei Chen
99
Body IVIM MRI
115
Chapter 14 IVIM Diffusion Model in Prostate Cancer Baris Turkbey Stephanie Harmon Marcin Czarniecki and Peter L Choyke
283
Chapter 15 Clinical Application of IVIM in the Female Pelvis Elaine Y P Lee and PekLan Khong
291
Chapter 16 IVIM MRI of the Placenta Paddy J Slator Jana Hutter Eleftheria Panagiotaki Mary A Rutherford Joseph V Hajnal and
317
Chapter 17 Fetal IVIM MRI András Jakab Raimund Kottke Ianina Scheer and Ruth Tuura
339
Chapter 18 IVIM MRI and Bone Marrow Robert Burns Sébastien Mulé Pierre Zerbib Alexandre Vignaud Emmanuel Itti Alain Rahmouni and Alain ...
359
Section IV Next Frontiers of IVIM MRI
373
Advantages Disadvantages and Analysis Pitfalls Gabrielle Fournet Luisa Ciobanu and Denis Le Bihan
375
Data Acquisition Modeling and Brain Applications André Ahlgren and Ronnie Wirestam
403

A General Overview Matthew R Orton Neil P Jerome Mihaela Rata and DowMu Koh
117
Chapter 7 Head and Neck IVIM MRI Takashi Nakamura and Misa Sumi
147
Chapter 8 IVIM MRI of the Breast Mami Iima and Masako Kataoka
173
Chapter 9 Cardiac IVIM MRI Zhiyong Li and Anna Mou
195
Chapter 10 Liver Fibrosis Shintaro Ichikawa and Utaroh Motosugi
205
Chapter 11 Assessment of Liver Tumors with IVIM DiffusionWeighted Imaging Stefanie J Hectors Sara Lewis and Bachir Taouli
219
Chapter 12 IVIM MRI of the Pancreas Miriam Klauß Philipp Mayer and Bram Stieltjes
245
Chapter 13 IVIM MRI in the Kidney Moritz J Schneider Mike Notohamiprodjo and Olaf Dietrich
261
Chapter 21 Flow Compensation and Modeling of IVIM MRI in the Liver and Pancreas Andreas Wetscherek
423
Arterial Spin Labeling Prepared IVIM Xingxing Zhang and Matthias J P van Osch
435
Chapter 23 Advanced Methods for IVIM Parameter Estimation Peter T While
449
Chapter 24 IVIM MRI Analysis with Low Perfusion Emma M Meeus and Andrew C Peet
485
Chapter 25 Synthetic and Physiological IVIM Complexity Eric E Sigmund
507
Index
525
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Autoren-Profil (2018)

Denis Le Bihan is a radiologist and physicist and inventor of the intravoxel incoherent motion (IVIM) concept and method. He is an MD and a PhD and is a member of the French Academy of Sciences and the French Academy of Technologies. He is also the founding director of NeuroSpin [an ultra-high field magnetic resonance imaging (MRI) facility in Saclay, France] and a visiting professor of the Kyoto University Graduate School of Medicine, Kyoto Prefectural University of Medicine, and the Japan National Institute of Physical Sciences, Okazaki.

Mami lima is a radiologist and assistant professor of diagnostic imaging and nuclear medicine at the Kyoto University Graduate School of Medicine and the Hakubi Center for Advanced Research, Kyoto University. She is an MD and a PhD and has published important articles about IVIM and diffusion MRI in the breast.

Christian Federau is a neuroradiologist and theoretical physicist and is working as an attending neuroradiologist at the University Hospital in Basel, Switzerland.

Eric E. Sigmund is an MRI physicist and associate professor of radiology at New York University (NYU) School of Medicine within NYU Langone Health in New York City.

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