Reactive Intermediate Chemistry

Cover
Robert A. Moss, Matthew S. Platz, Maitland Jones, Jr.
John Wiley & Sons, 07.01.2004 - 1080 Seiten
Reactive Intermediate Chemistry presents a detailed and timely examination of key intermediates central to the mechanisms of numerous organic chemical transformations. Spectroscopy, kinetics, and computational studies are integrated in chapters dealing with the chemistry of carbocations, carbanions, radicals, radical ions, carbenes, nitrenes, arynes, nitrenium ions, diradicals, etc. Nanosecond, picosecond, and femtosecond kinetic realms are explored, and applications of current dynamics and electronic structure calculations are examined.

Reactive Intermediate Chemistry provides a deeper understanding of contemporary physical organic chemistry, and will assist chemists in the design of new reactions for the efficient synthesis of pharmaceuticals, fine chemicals, and agricultural products. Among its features, this authoritative volume is:

  • Edited and authored by world-renowned leaders in physical organic chemistry.
  • Ideal for use as a primary or supplemental graduate textbook for courses in mechanistic organic chemistry or physical chemistry.
  • Enhanced by supplemental reading lists and summary overviews in each chapter.
 

Inhalt

Carbocations
4
Reactivity of Carbocations
15
Carbocations 3
29
Conclusion and Outlook
35
Crossing the Borderline Between
44
Aliphatic Nucleophilic Substitution at Tertiary Carbon
59
Conclusion and Outlook
65
Carbanions
70
Conclusion and Outlook
261
Singlet Carbenes
273
Stable Singlet Carbenes
329
Triplet Carbenes
375
Atomic Carbon
463
Nitrenes
501
Synthetic Carbene and Nitrene Chemistry
561
Nitrenium Ions
593

Carbanions
74
Basicity of CarbanionsAcidity of Carbon Acids
76
Reactivity
97
Radicals
122
Multistep Radical Reactions
134
Elementary Radical Reactions
140
Conclusion and Outlook
157
Radicals 121
163
NonKekulé Molecules
166
Electron Spin or Paramagnetic Resonance Spectroscopy in Matrices
172
INTRODUCTION
200
Organic Radical Ions
206
Historical CommentsOrigins of Radical Ion Chemistry
207
Radical Ion Structures
214
Relationships with Other Intermediates
234
Silylenes and Germylenes Stannylenes Plumbylenes
651
Structures
718
Structures of Strained Hydrocarbons
724
Structures Stability
728
Reactivity of Strained Hydrocarbons Toward External Reagents
733
Arynes
741
Matrix Isolation
797
A Tool
847
The Picosecond Realm
873
Reactions on the Femtosecond Time Scale
899
Potential Energy Surfaces and Reaction Dynamics
925
The Partnership between Electronic Structure Calculations
961
Index
1005
Urheberrecht

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Autoren-Profil (2004)

Robert A. Moss is the Louis P. Hammett Professor of Chemistry at Rutgers, the State University of New Jersey, New Brunswick, NJ. He received his Ph. D. with Professor Gerhard Closs (Chicago) and was a postdoctoral student with Professor Ronald Breslow (Columbia). Dr. Moss has been an A.P. Sloan Foundation Fellow, and a visiting professor or scientist at M.I.T., the University of Oxford, the Politechnika (Warsaw), the Weizmann Institute, the National Research Council of Canada, and the Hebrew University of Jerusalem. He has more than 350 scientific publications in the areas of reactive intermediates and chemistry in molecular aggregates.

Matthew S. Platz was born in New York City and graduated from the State University of NY at Albany ( B.Sc. in Chemistry and Mathematics) in 1973 and obtained his Ph.D. in Chemistry studying with Professor Jerome Berson in 1976. After a postdoctoral stint with Professor Gerhard Closs, Platz joined the faculty of The Ohio State University in 1978 where he has spent his entire independent career. Platz served as chair of the OSU Chemistry Department from 1994-1999, was the Melvin S. Newman Professor (1994-2001), and was named Distinguished University Professor in 2001. Platz has been a Sloan Fellow, a Camille and Henry Dreyfus Teacher-Scholar, and a Cope Scholar of the American Chemical Society. He has over 200 scientific publications and holds over a dozen patents.

Maitland Jones, Jr. turned to chemistry only after the invention of the curveball by his peers made it clear that he would never be a major league centerfielder. He received his B.S. degree from Yale College and his M. S. and Ph. D. degrees from Yale University, where he studied with William von E. Doering. After a postdoctoral year with Jerry Berson at Wisconsin he came to Princeton in 1964 as an Instructor. He has been there ever since, and is now David B. Jones Professor of Chemistry. He has been a visiting professor at Columbia and Harvard in this country, as well as at the Vrije Universiteit in Holland, the Kiev Polytechnic in Ukraine, and Fudan University in the People's Republic of China. He recently spent three months in Basel as the Freiwillige Akademische Gesellschaft Professor. He and his wife, the artist Susan Hockaday, were comasters of Stevenson Hall, one of Princeton's undergraduate colleges, for several years. Together with the members of his research group, he has published more than 200 papers centered on the chemistry of reactive intermediates, as well as a recent textbook on organic chemistry.

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