Handbook of Research on Systems Biology Applications in MedicineDaskalaki, Andriani IGI Global, 30.11.2008 - 982 Seiten Systems biology is the study of the interactions between the components of a biological system and the way these interactions lead to a specific function and behavior of that system. The Handbook of Research on Systems Biology Applications in Medicine presents concepts of the applications of systems biology in medicine, leading students and advanced researchers to an understanding of current ideas in the complex field of systems biology, analysis of data, and development of models, simulation, and drug development. With over 50 incisive research contributions from international experts, this unsurpassed compendium of critical research is an indispensable resource for medical libraries worldwide. |
Inhalt
1 | |
Systems and Control Theory for Medical Systems Biology | 11 |
Mathematical Description of Time Delays in Pathways Cross Talk | 27 |
Deterministic Modeling in Medicine | 74 |
Synthetic Biology as a Proof of Systems Biology | 97 |
Computational Models for the Analysis of Modern Biological Data | 117 |
Computer Aided Knowledge Discovery in Biomedicine | 126 |
Phylogenetic Profiling | 143 |
Development of Specific Gamma Secretase Inhibitors | 423 |
In Machina Systems for the Rational De Novo Peptide Design | 438 |
Applications of Metabolic Flux Balancing in Medicine | 458 |
MultiLevel Data Integration and Data Mining in Systems Biology | 476 |
Methods for Reverse Engineering of Gene Regulatory Networks | 497 |
Data Integration for Regulatory Gene Module Discovery | 516 |
Discrete Networks as a Suitable Approach for the Analysis of Genetic Regulation | 530 |
A Review of Signal Processing Approaches | 541 |
Computational Methods for the Prediction of GPCRs Coupling Selectivity | 167 |
A Common Structural Theme Implicated in a Wide Variety of Functional Roles | 182 |
Clustering Methods for GeneExpression Data | 209 |
Uncovering Fine Structure in Gene Expression Profile by Maximum Entropy Modeling of cDNA Microarray Images and Kernel Density Methods | 221 |
Gene Expression Profiling with the BeadArray Platform | 239 |
The Affymetrix GeneChip Microarray Platform | 251 |
Alternative Isoform Detection Using Exon Arrays | 262 |
Gene Expression in Microbial Systems for Growth and Metabolism | 278 |
Alternative Splicing and Disease | 291 |
Mathematical Modeling of the Aging Process | 312 |
A Model of Hormonal Aging | 331 |
Systems Biology Applied to Cancer Research | 339 |
Systems Biology Strategies in Studies of Energy Homeostasis In Vivo | 354 |
Approaching Type 2 Diabetes Mellitus by Systems Biology | 361 |
Systems Biology and Infectious Diseases | 377 |
Systems Biology of HumanPathogenic Fungi | 403 |
Open Source Software for Population Analysis | 556 |
How Proteins Control Excitation Energy Transfer | 573 |
A Systems Biology Approach | 588 |
Modeling of Porphyrin Metabolism with PyBioS | 643 |
Interference Microscopy for Cellular Studies | 656 |
Fluorescence Imaging of Mitochondrial LongTerm Depolarization in Cancer Cells Exposed to HeatStress | 673 |
Protein Interactions and Diseases | 694 |
The Reactome Perspective | 714 |
Entropy and Thermodynamics in Biomolecular Simulation | 731 |
Model Development and Decomposition in Physiology | 759 |
A Pandemic Avian Influenza Mathematical Model | 798 |
A Mathematical Model with Immunization Program | 809 |
Automated Image Analysis Approaches in Histopathology | 826 |
About the Contributors | 851 |
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Andere Ausgaben - Alle anzeigen
Handbook of Research on Systems Biology Applications in Medicine, Band 2 Keine Leseprobe verfügbar - 2009 |
Handbook of Research on Systems Biology Applications in Medicine, Band 1 Andriani Daskalaki Keine Leseprobe verfügbar - 2009 |
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